Protein Design Intern: Computational Bioinformatics

Syngenta Group; Durham (NC); On-site; USD 28,000 - 62,000; Full time

Benefits offered by this job

Competitive wages

Professional development

Work-life balance

Job summary

Syngenta Seeds Field Crops in Durham, NC seeks a Protein Design Intern to work on computational protein design within a high-performance scientific team. You will contribute to cutting-edge solutions for agricultural biotechnology and gain hands-on experience in a collaborative program.

The role offers exposure to day-to-day operations, opportunities to apply academic knowledge, and development of professional skills in a supportive, interdisciplinary environment.

Qualifications

• MS or PhD student in Bioinformatics, Computational Biology, Structural Biology, or related field.
• Proficiency in Python and/or R for bioinformatics; PyRosetta a plus.
• Familiarity with protein structure prediction methods (AlphaFold2, ESMFold, Boltz).
• Familiarity with protein structure visualization (PyMOL or ChimeraX).
• Experience with Linux/Unix command-line environments.
• Knowledge of sequence analysis tools (BLAST, alignment methods).

Responsibilities

• Apply structural bioinformatics methods to discover novel proteins.
• Develop computational workflows that integrate sequence- and structure-based search algorithms to identify and rank protein candidates.
• Leverage protein structure-based search workflows using FoldSeek, ESMFold, and Boltz.
• Perform structural analysis and annotation of protein candidates.
• Develop Python/Bash scripts for data processing and visualization.
• Document workflows, create user guides, and present findings to cross-functional teams.
• Collaborate with other scientists to refine research strategies based on biological insights.
• Share results and learnings at team meetings and educate team members on workflows and results.

Skills

Python

R

PyRosetta

Linux

BLAST

Sequence analysis

Education

MS/PhD candidate

Tools

FoldSeek

ESMFold

Boltz

PyMOL

ChimeraX

Job description

Syngenta Seeds Field Crops in Durham, NC seeks a Protein Design Intern to work on computational protein design within a high-performance scientific team. You will contribute to cutting-edge solutions for agricultural biotechnology and gain hands-on experience in a collaborative program.

The role offers exposure to day-to-day operations, opportunities to apply academic knowledge, and development of professional skills in a supportive, interdisciplinary environment.