Procurement Manager

AI Chopping Block; South San Francisco, Northern (CA, KY); Hybrid; USD 124,000 - 155,000; Full time

Benefits offered by this job

Base salary, bonus, and equity

Job summary

Xaira Therapeutics is seeking a Procurement Manager to lead end-to-end procurement, drive an AI-enabled operation, and transform supplier engagements. You will partner with scientists, engineers, and business leads to build a world-class procurement function.

The role emphasizes contract-first CLM adoption, data integrity, and scalable supplier relationships, with a base salary in SF Bay Area plus bonus and equity. We value entrepreneurial, stakeholder-focused leadership.

Qualifications

• 5+ years in procurement, strategic sourcing, or supply chain in biotech, pharma, or tech.
• Proven negotiation results on complex service agreements (CRO, services, and technology).
• Hands-on with modern procurement tools (Ironclad, Coupa, NetSuite, Ramp) and curiosity about what replaces them.
• Practical AI fluency applied to real workflows — you can point to processes you've automated.
• Strong analytics: spend analysis, dashboarding, supplier ecosystems, advanced metrics and analytics giving Xaira leverage as a competitive advantage among Xaira’s peer group.

Responsibilities

• Own end-to-end procurement operations: P2P process, sourcing, and technology enablement across all goods and services
• Drive adoption of our contract-first CLM framework while reducing cycle times
• Run procurement as a service business, with stakeholder experience as a core focus
• Support Accounting: PO hygiene, invoice-match resolution, accruals, vendor master data and close activities
• Pilot and scale AI across the lifecycle: contract analysis, spend classification, supplier intelligence, negotiation prep, workflow automation
• Make Xaira's procurement a showcase for AI-augmented operations — measured in cycle time, coverage, and cost
• Translate the emerging procure-tech landscape into practical and adopted tooling
• Lead sourcing events and negotiations across core life-sciences suppliers
• Structure agreements that protect Xaira's flexibility: competitive tension, cancellation frameworks and leading engagement terms
• Build supplier relationships that scale: performance management, risk monitoring and strategic partnerships
• Drive build-vs-buy decisions across the stack (P2P, CLM, sourcing, cost savings/avoidance) with lean, high-leverage solutions
• Build spend analytics that turn data into decisions: category insights, supplier concentration, budget-to-actual
• Own data integrity across procurement and P2P systems

Skills

Procurement

Strategic sourcing

Supply chain

Negotiation

AI fluency

Analytics

Tools

Ironclad

Coupa

NetSuite

Ramp

Job description

About Xaira Therapeutics

Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.

The Role

Xaira is seeking a Procurement Manager at the leading edge of the function — a builder who treats procurement as a commercial engine and a proving ground for AI-enabled operations. You're obsessed with stakeholders: scientists, engineers, and business partners are your customers, and their success is your scoreboard. You'll inherit a strong foundation but you have an obsession to drive the function beyond the empirical high-bar.

What You'll Do

Operations Leadership

• Own end-to-end procurement operations: P2P process, sourcing, and technology enablement across all goods and services
• Drive adoption of our contract-first CLM framework while reducing cycle times
• Run procurement as a service business, with stakeholder experience as a core focus
• Support Accounting: PO hygiene, invoice-match resolution, accruals, vendor master data and close activities

AI Enablement

• Pilot and scale AI across the lifecycle: contract analysis, spend classification, supplier intelligence, negotiation prep, workflow automation
• Make Xaira's procurement a showcase for AI-augmented operations — measured in cycle time, coverage, and cost
• Translate the emerging procure-tech landscape into practical and adopted tooling

Supplier Engagement & Negotiations

• Lead sourcing events and negotiations across core life-sciences suppliers
• Structure agreements that protect Xaira's flexibility: competitive tension, cancellation frameworks and leading engagement terms
• Build supplier relationships that scale: performance management, risk monitoring and strategic partnerships

Procure-Tech, Data & Analytics

• Drive build-vs-buy decisions across the stack (P2P, CLM, sourcing, cost savings/avoidance) with an emphasis toward lean, high-leverage solutions
• Build spend analytics that turn data into decisions: category insights, supplier concentration, budget-to-actual
• Own data integrity across procurement and P2P systems

What You Bring

• 5+ years in procurement, strategic sourcing, or supply chain; biotech, pharma, or high-growth tech preferred
• Proven negotiation results on complex service agreements (CRO, services, and technology)
• Hands-on with modern procurement tools (Ironclad, Coupa, NetSuite, Ramp) and curiosity about what replaces them
• Practical AI fluency applied to real workflows — you can point to processes you've automated
• Strong analytics: spend analysis, dashboarding, supplier ecosystems, advanced metrics and analytics giving Xaira leverage as a competitive advantage among Xaira’s peer group
• Stakeholder obsession - Building trust through accountability and delivery making Procurement an invaluable business partnership
• Concise, executive-ready communication
• Entrepreneurial: you find the gap, propose the fix, and ship it

Why This Role Matters

Every dollar and every week Procurement saves is capacity redirected toward discovering new medicines. If you want to build the most advanced Procurement function in biotech, this is the seat.

Compensation

We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. We offer a competitive package that includes base salary, bonus, and equity. The base pay range for this position is expected to be $124,000 - $155,000 annually; however, the base pay offered may vary depending on the market, job-related knowledge, skills and capabilities, and experience.

Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.