Procurement Manager

Xaira; South San Francisco (CA); On-site; USD 124,000 - 155,000; Full time

Job summary

Xaira Therapeutics is seeking a Procurement Manager to lead end-to-end procurement, leverage AI-enabled operations, and build a scalable supplier network. You will partner with scientists, engineers, and business teams to deliver value, reduce cycle times, and implement a contract-first CLM framework across P2P and sourcing.

The role emphasizes analytics, stakeholder collaboration, and entrepreneurial impact.

Qualifications

• 5+ years in procurement, strategic sourcing, or supply chain; biotech, pharma, or high-growth tech preferred.
• Proven negotiation results on complex service agreements (CRO, services, and technology).
• Hands-on with modern procurement tools (Ironclad, Coupa, NetSuite, Ramp) and curiosity about what replaces them.
• Practical AI fluency applied to real workflows — you can point to processes you've automated.
• Strong analytics: spend analysis, dashboarding, supplier ecosystems, advanced metrics and analytics giving Xaira leverage as a competitive advantage.

Responsibilities

• Own end-to-end procurement operations: P2P process, sourcing, and technology enablement across all goods and services
• Drive adoption of our contract-first CLM framework while reducing cycle times
• Run procurement as a service business, with stakeholder experience as a core focus
• Support Accounting: PO hygiene, invoice-match resolution, accruals, vendor master data and close activities
• Pilot and scale AI across the lifecycle: contract analysis, spend classification, supplier intelligence, negotiation prep, workflow automation
• Make Xaira's procurement a showcase for AI-augmented operations — measured in cycle time, coverage, and cost
• Translate the emerging procure-tech landscape into practical and adopted tooling
• Lead sourcing events and negotiations across core life-sciences suppliers
• Structure agreements that protect Xaira's flexibility: competitive tension, cancellation frameworks and leading engagement terms
• Build supplier relationships that scale: performance management, risk monitoring and strategic partnerships
• Drive build-vs-buy decisions across the stack (P2P, CLM, sourcing, cost savings/avoidance) with lean, high-leverage solutions
• Build spend analytics that turn data into decisions: category insights, supplier concentration, budget-to-actual
• Own data integrity across procurement and P2P systems

Skills

Procurement

Strategic sourcing

Negotiation

AI fluency

Analytics

Stakeholder management

Entrepreneurial mindset

Supplier engagement

Tools

Ironclad

Coupa

NetSuite

Ramp

Job description

About Xaira Therapeutics

Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.

The Role

Xaira is seeking a Procurement Manager at the leading edge of the function — a builder who treats procurement as a commercial engine and a proving ground for AI-enabled operations. You're obsessed with stakeholders: scientists, engineers, and business partners are your customers, and their success is your scoreboard. You'll inherit a strong foundation but you have an obsession to drive the function beyond the empirical high-bar.

What You'll Do

Operations Leadership

• Own end-to-end procurement operations: P2P process, sourcing, and technology enablement across all goods and services
• Drive adoption of our contract-first CLM framework while reducing cycle times
• Run procurement as a service business, with stakeholder experience as a core focus
• Support Accounting: PO hygiene, invoice-match resolution, accruals, vendor master data and close activities

AI Enablement

• Pilot and scale AI across the lifecycle: contract analysis, spend classification, supplier intelligence, negotiation prep, workflow automation
• Make Xaira's procurement a showcase for AI-augmented operations — measured in cycle time, coverage, and cost
• Translate the emerging procure-tech landscape into practical and adopted tooling

Supplier Engagement & Negotiations

• Lead sourcing events and negotiations across core life-sciences suppliers
• Structure agreements that protect Xaira's flexibility: competitive tension, cancellation frameworks and leading engagement terms
• Build supplier relationships that scale: performance management, risk monitoring and strategic partnerships

Procure-Tech, Data & Analytics

• Drive build-vs-buy decisions across the stack (P2P, CLM, sourcing, cost savings/avoidance) with an emphasis toward lean, high-leverage solutions
• Build spend analytics that turn data into decisions: category insights, supplier concentration, budget-to-actual
• Own data integrity across procurement and P2P systems

What You Bring

• 5+ years in procurement, strategic sourcing, or supply chain; biotech, pharma, or high-growth tech preferred
• Proven negotiation results on complex service agreements (CRO, services, and technology)
• Hands-on with modern procurement tools (Ironclad, Coupa, NetSuite, Ramp) and curiosity about what replaces them
• Practical AI fluency applied to real workflows — you can point to processes you've automated
• Strong analytics: spend analysis, dashboarding, supplier ecosystems, advanced metrics and analytics giving Xaira leverage as a competitive advantage among Xaira’s peer group
• Stakeholder obsession - Building trust through accountability and delivery making Procurement an invaluable business partnership
• Entrepreneurial: you find the gap, propose the fix, and ship it

Why This Role Matters

Every dollar and every week Procurement saves is capacity redirected toward discovering new medicines. If you want to build the most advanced Procurement function in biotech, this is the seat.

Compensation

We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. We offer a competitive package that includes base salary, bonus, and equity. The base pay range for this position is expected to be $124,000 - $155,000 annual; however, the base pay offered may vary depending on the market, job-related knowledge, skills and capabilities, and experience.

Xaira Therapeutics an equal-opportunity employer. We believe that our strength is in our differences. Our goal to build a diverse and inclusive team began on day one, and it will never end.

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.

As set forth in Xaira Therapeutics’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.