Process Engineer

Elevait Solutions LLC; Milwaukee (WI); Presencial; USD 65 000 - 90 000; Tempo integral

Resumo da oferta

Elevait Solutions LLC is seeking a Bioprocess Research Associate (AAV Gene Therapy) to join our Research Triangle Park team. The role focuses on running rAAV manufacturing and GLP-grade studies, scaling from small to pilot processes, and maintaining tight batch records.

You will culture cells, perform purification steps, and document data in real time while supporting investigations and protocol development. Onsite in RTP, 12-month contract, with strong emphasis on hands-on lab work.

Qualificações

• BS or MS in biotechnology, chemistry, biochemistry, or biochemical/chemical engineering with hands-on lab experience.
• Experience with upstream or downstream bioprocess operations and accurate documentation.

Responsabilidades

• Run defined rAAV manufacturing and GLP-grade studies per protocols and batch records.
• Grow and maintain cell cultures and produce vector at small and pilot scale.
• Execute centrifugation, filtration, chromatography, and related purification steps.
• Record lab work and data in real time and help complete batch records.
• Support manufacturing investigations with data and write technical reports.

Conhecimentos

Upstream bioprocessing

Downstream purification

Protocol execution

Formação académica

Bachelor's or Master's in biotechnology/chemistry/biochemistry/engineering

Descrição da oferta de emprego

Job Title: Bioprocess Research Associate (AAV Gene Therapy)
Industry: Biotechnology
Location: Research Triangle Park, NC

Duration:12 months

Client Overview

Our client is a gene therapy company headquartered in Research Triangle Park and owned by a global pharmaceutical and life sciences company. It develops AAV-based gene therapies using its own proprietary cell line manufacturing platform, with programs ranging from early research to late-stage clinical trials. This role supports the team that makes vector material for research and GLP studies.

Top 3 Skills

• Upstream bioprocessing: mammalian cell culture and vector production in shake flasks, rocking-motion bioreactors, and stirred-tank bioreactors
• Downstream purification: centrifugation, filtration, and chromatography
• Protocol- and batch-record-driven execution with real-time GLP and GDP documentation

What You'll Do

• Run defined rAAV manufacturing and lab activities for research and GLP-grade studies, following protocols and batch records
• Grow and maintain cell cultures, and produce vector at small and pilot scale
• Run centrifugation, filtration, chromatography, and related purification steps
• Execute process characterization and robustness experiments assigned by MSAT and process development scientists
• Record lab work and data in real time in paper or electronic systems, and help complete and review batch records
• Run confirmatory experiments and collect data to support manufacturing investigations
• Help write technical protocols, experiment reports, and summary presentations
• Set up, operate, and maintain lab equipment, and keep the lab inspection-ready
• Coordinate materials, consumables, and reagents with lab management and solution prep teams
• Share progress and results with project stakeholders

What We Need From You

• A BS in biotechnology, chemistry, biochemistry, or chemical or biochemical engineering with 2+ years of lab research or biologics manufacturing experience, or an MS in one of those fields with any amount of experience
• Hands-on experience with upstream or downstream bioprocess operations
• Experience executing experiments under direction from protocols and batch records, with accurate documentation
• Ability to work fully onsite in Research Triangle Park, including periodic weekend coverage
• A desire to stay in a hands-on, lab-focused role rather than a design or management track

Preferred / Bonus

• AAV or other viral vector production experience
• cGMP manufacturing or manufacturing-support lab experience
• WAVE bioreactor or stirred-tank bioreactor experience, including scale-up, scale-down, or process characterization runs
• Background in MSAT, process development, or biologics manufacturing