Process Development Associate Scientist – Cell Therapy

Cabaletta Bio; Philadelphia (Philadelphia County); On-site; USD 90,000 - 130,000; Full time

Benefits offered by this job

Health insurance

Retirement plan

Paid time off

Stock options

Job summary

Cabaletta Bio in Philadelphia is seeking an Associate Scientist, Process Development to refine, develop, and transfer processes for cell therapy candidates. You will collaborate with MSAT, Analytical Development, QA, Regulatory, and CDMOs, with travel up to 10% and potential overtime.

You will execute DoE studies, support QbD-driven production, and help ensure CGMP compliance and data integrity across batches.

Qualifications

• B.S. with 3+ years or M.S. with 1+ years in process development and manufacturing under cGMP.
• Experience with T-cells or immunological cell therapies.
• Experience in cell therapy manufacturing scale up and technology transfer.
• Good knowledge of cGMP biopharma manufacturing and ICH regulations.
• Strong coordination and communication skills; highly organized.

Responsibilities

• Execute process development experiments and report results to teams.
• Design and conduct DoE studies to evaluate CQAs and process performance.
• Support cell therapy production using QbD principles.
• Assist transfer of processes to CDMOs for clinical manufacturing.
• Develop and review eBRs to ensure GMP alignment.
• Capture data timely with integrity and protocol compliance.
• Maintain training compliance for manufacturing staff.
• Identify new technologies to reduce costs and increase throughput.
• Coordinate with internal groups and external partners for shipping samples.
• Manage laboratory material inventory and planning needs.

Skills

Coordination

Communication

Problem-solving

Independent work

Education

B.S. or M.S. in a relevant field

Job description

Cabaletta Bio in Philadelphia is seeking an Associate Scientist, Process Development to refine, develop, and transfer processes for cell therapy candidates. You will collaborate with MSAT, Analytical Development, QA, Regulatory, and CDMOs, with travel up to 10% and potential overtime.

You will execute DoE studies, support QbD-driven production, and help ensure CGMP compliance and data integrity across batches.