Principal System Architect - Photon Flash

onehealthineers; United States; On-site; USD 224,000 - 309,000; Full time

Benefits offered by this job

Medical insurance

Dental insurance

Vision insurance

401(k) retirement plan

Life insurance

Long-term and short-term disability

Paid parking/public transportation

Paid time off

Paid sick and safe time

Job summary

Siemens Healthineers is seeking a Principal System Architect to define the architecture for an investigational Photon FLASH radiation therapy platform for clinical trials.

The role bridges clinical relevance and technical framework across software and hardware, coordinating radiobiology, physics, and treatment optimization to deliver safe, scalable FLASH capabilities for future clinical investigation.

Qualifications

• Ph.D. required in Physics, Medical Physics, Biomedical Engineering, Systems Engineering or Electrical Engineering.
• 10+ years of experience developing complex medical devices, treatment planning systems or other regulated healthcare technologies.
• Ability to translate clinical requirements into technology requirements.

Responsibilities

• Define the overall architecture and technical roadmap for the Photon FLASH ecosystem.
• Translate requirements from radiobiology, clinical viability, physics, dose-rate modeling, and treatment optimization into system requirements and product features.
• Lead system-level decisions across treatment planning, radiation delivery, controls, delivery software, planning software and clinical workflow.
• Guide development of FLASH planning and delivery capabilities balancing clinical needs, technical constraints, safety and performance; manage system-level risk and design trade-offs.
• Ensure alignment with FDA design controls and applicable standards.
• Collaborate with clinicians, medical physicists, KOLs, academic partners, and ARPA-H stakeholders to shape future clinical use cases and study requirements.

Skills

Systems engineering

Cross-functional leadership

Medical device development

Regulatory knowledge

Requirements translation

Education

Ph.D in Physics/Medical Physics/Biomedical/Systems/Electrical Eng

Job description

Join us in pioneering breakthroughs in healthcare. For everyone. Everywhere. Sustainably.

Our inspiring and caring environment forms a global community that celebrates diversity and individuality. We encourage you to step beyond your comfort zone, offering resources and flexibility to foster your professional and personal growth, all while valuing your unique contributions.

We are seeking a Principal System Architect to define the architecture for an investigational Photon FLASH radiation therapy platform suitable for clinical trials. This role is critical to the success of the ARPA-H Photon FLASH program as it will establish the bridge between clinical relevance and the technical framework that guides both software and hardware development.

You will translate emerging FLASH science into an integrated system architecture spanning treatment planning, radiation delivery, imaging, controls, workflow, and data systems. Working across preclinical, clinical, scientific and engineering disciplines, you will ensure novel FLASH capabilities are clinically relevant, technically feasible, and suitable for future clinical investigation and productization.

Key Responsibilities

• Define the overall architecture and technical roadmap for the Photon FLASH ecosystem in the face of challenging and changing requirements and realization technologies
• Translate requirements from radiobiology, clinical viability, radiation physics, dose-rate modeling, and treatment optimization into system requirements and product features
• Lead system-level decisions across treatment planning, radiation delivery, controls, delivery software, planning software, and clinical workflow
• Guide development of FLASH treatment planning and delivery capabilities that balance clinical needs, technical constraints, safety, and performanceLead system-level risk management, hazard analysis, and design trade-offs
• Ensure alignment with FDA design controls and applicable standards
• Collaborate with clinicians, medical physicists, Key Opinion Leaders, academic partners, and ARPA-H stakeholders to shape future clinical use cases and study requirements

Qualifications

• Ph.D in Physics, Medical Physics, Biomedical Engineering, Systems Engineering, or Electrical Engineering
• 10+ years of experience developing complex medical devices, treatment planning systems, radiation therapy platforms, or other regulated healthcare technologies
• Is guided by maturity, vision, depth of domain and technical experience and the ability to identify, analyze, and decide on relevant issues in time and with courage, even in the absence of complete information
• Ability to transfer clinical needs and protocols into technology requirements
• Strong systems engineering background with experience leading multidisciplinary product development
• Deep understanding of radiation therapy treatment planning, optimization, and delivery systems
• Experience with medical device risk management, regulatory requirements, and design controls
• Excellent technical leadership and cross-functional communication skills

Who we are :

We are a team of more than 72,000 highly dedicated Healthineers in more than 70 countries. As a leader in medical technology, we constantly push the boundaries to create better outcomes and experiences for patients, no matter where they live or what health issues they are facing. Our portfolio is crucial for clinical decision-making and treatment pathways.

How we work:

When you join Siemens Healthineers, you become one in a global team of scientists, clinicians, developers, researchers, professionals, and skilled specialists, who believe in each individual's potential to contribute with diverse ideas. We are from different backgrounds, cultures, religions, political and/or sexual orientations, and work together, to fight the world's most threatening diseases and enable access to care, united by one purpose: to pioneer breakthroughs in healthcare. For everyone. Everywhere. Sustainably.

To find out more about Siemens Healthineers businesses, please visit our company page here .

The base pay range for this position is:

$224,490 - $308,671

Factors which may affect starting pay within this range may include geography/market, skills, education, experience, and other qualifications of the successful candidate.

If this is a commission eligible position the commission eligibility will be in accordance with the terms of the Company's plan. Commissions are based on individual performance and/or company performance.

The Company offers the following benefits for this position, subject to applicable eligibility requirements:

• medical insurance
• dental insurance
• vision insurance
• 401(k) retirement plan
• life insurance
• long-term and short-term disability insurance
• paid parking/public transportation
• paid time off
• paid sick and safe time

Equal Employment Opportunity Statement: Siemens Healthineers is an Equal Opportunity and Aff… All q