Principal System Architect - Photon Flash

Siemens Healthineers in; Palo Alto (CA); On-site; USD 224,000 - 309,000; Full time

Benefits offered by this job

Medical insurance

Dental insurance

Vision insurance

401(k) retirement plan

Life insurance

Disability insurance

Paid time off

Paid sick time

Job summary

Siemens Healthineers in Palo Alto is seeking a Principal System Architect to define the architecture for an investigational Photon FLASH radiation therapy platform for clinical trials. This role bridges clinical needs and technical frameworks across software and hardware.

You will collaborate across preclinical, clinical, scientific and engineering teams to ensure FLASH capabilities are clinically relevant, technically feasible, and ready for future investigation and productization.

Qualifications

• Ph.D. in a physics/engineering field relevant to medical devices.
• Experience with regulated healthcare technology and complex devices.
• Ability to translate clinical needs into technical requirements.
• Strong leadership in multidisciplinary product development.

Responsibilities

• Define architecture and roadmap for the Photon FLASH ecosystem.
• Translate radiobiology and clinical needs into system requirements.
• Lead system-level decisions across planning, delivery, controls, software, and workflow.
• Guide FLASH treatment planning and delivery capabilities balancing safety and performance.
• Lead system-level risk management and hazard analysis.
• Ensure alignment with FDA design controls and applicable standards.
• Collaborate with clinicians, KOLs, and ARPA-H stakeholders to shape study requirements.

Skills

Technical leadership

Systems engineering

Cross-functional collaboration

Regulatory understanding

Clinical translation

Radiation therapy knowledge

Problem solving

Education

PhD in Physics / Medical Physics / Biomedical Engineering / Systems Engineering / Electrical Engineering

Job description

Principal System Architect - Photon Flash (Finance)

Join us in pioneering breakthroughs in healthcare. For everyone. Everywhere. Sustainably.

Our inspiring and caring environment forms a global community that celebrates diversity and individuality. We encourage you to step beyond your comfort zone, offering resources and flexibility to foster your professional and personal growth, all while valuing your unique contributions.

We are seeking a Principal System Architect to define the architecture for an investigational Photon FLASH radiation therapy platform suitable for clinical trials. This role is critical to the success of the ARPA-H Photon FLASH program as it will establish the bridge between clinical relevance and the technical framework that guides both software and hardware development.

You will translate emerging FLASH science into an integrated system architecture spanning treatment planning, radiation delivery, imaging, controls, workflow, and data systems. Working across preclinical, clinical, scientific and engineering disciplines, you will ensure novel FLASH capabilities are clinically relevant, technically feasible, and suitable for future clinical investigation and productization.

Key Responsibilities

• Define the overall architecture and technical roadmap for the Photon FLASH ecosystem in the face of challenging and changing requirements and realization technologies
• Translate requirements from radiobiology, clinical viability, radiation physics, dose-rate modeling, and treatment optimization into system requirements and product features
• Lead system-level decisions across treatment planning, radiation delivery, controls, delivery software, planning software, and clinical workflow
• Guide development of FLASH treatment planning and delivery capabilities that balance clinical needs, technical constraints, safety, and performance
• Lead system-level risk management, hazard analysis, and design trade-offs
• Ensure alignment with FDA design controls and applicable standards
• Collaborate with clinicians, medical physicists, Key Opinion Leaders, academic partners, and ARPA-H stakeholders to shape future clinical use cases and study requirements

Qualifications

• Ph.D in Physics, Medical Physics, Biomedical Engineering, Systems Engineering, or Electrical Engineering
• 10+ years of experience developing complex medical devices, treatment planning systems, radiation therapy platforms, or other regulated healthcare technologies
• Is guided by maturity, vision, depth of domain and technical experience and the ability to identify, analyze, and decide on relevant issues in time and with courage, even in the absence of complete information
• Ability to transfer clinical needs and protocols into technology requirements
• Strong systems engineering background with experience leading multidisciplinary product development
• Deep understanding of radiation therapy treatment planning, optimization, and delivery systems
• Experience with medical device risk management, regulatory requirements, and design controls
• Excellent technical leadership and cross-functional communication skills

Who we are

We are a team of more than 72,000 highly dedicated Healthineers in more than 70 countries. As a leader in medical technology, we constantly push the boundaries to create better outcomes and experiences for patients, no matter where they live or what health issues they are facing. Our portfolio is crucial for clinical decision-making and treatment pathways.

How we work:

When you join Siemens Healthineers, you become one in a global team of scientists, clinicians, developers, researchers, professionals, and skilled specialists, who believe in each individual's potential to contribute with diverse ideas. We are from different backgrounds, cultures, religions, political and/or sexual orientations, and work together, to fight the world's most threatening diseases and enable access to care, united by one purpose: to pioneer breakthroughs in healthcare. For everyone. Everywhere. Sustainably.

To find out more about Siemens Healthineers businesses, please visit our company page here.

The base pay range for this position is:

$224,490 - $308,671

Factors which may affect starting pay within this range may include geography/market, skills, education, experience, and other qualifications of the successful candidate.

If this is a commission eligible position the commission eligibility will be in accordance with the terms of the Company's plan. Commissions are based on individual performance and/or company performance.

The Company offers the following benefits for this position, subject to applicable eligibility requirements: medical insurance, dental insurance, vision insurance, 401(k) retirement plan. life insurance, long-term and short-term disability insurance, paid parking/public transportation, paid time off, paid sick and safe time.

Equal Employment Opportunity Statement: Siemens Healthineers is an Equal Opportunity and 1st or continuing Employment Opportunity Employer encouraging diversity in the workplace. All qualified applicants will receive consideration for employment without regard to their race, color, creed, religion, national origin, citizenship status, ancestry, sex, age, physical or mental disability unrelated to ability, marital status, family responsibilities, pregnancy, genetic information, sexual orientation, gender expression, gender identity, transgender, sex stereotyping, order of protection status, protected veteran or military status, or an unfavorable discharge from military service, and other categories protected by federal, state or local law.

EEO is the Law: Applicants and employees are protected under Federal law from discrimination. To learn more, click here.

Reasonable Accommodations: Siemens Healthineers is committed to equal employment opportunity. As part of this commitment, we will ensure that persons with disabilities are provided reasonable accommodations.

California Privacy Notice: California residents have the right to receive additional notices about their personal information. To learn more, click here.

Export Control: "A successful candidate must be able to work with controlled technology in accordance with US export control law." "It is Siemens Healthineers' policy to comply fully and completely with all United States export control laws and regulations, including those implemented by the Department of Commerce through the Export Administration Regulations (EAR), by the Department of State through the International Traffic in Arms Regulations (ITAR), and by the Treasury Department through the Office of Foreign Assets Control (OFAC) sanctions regulations."

To all recruitment agencies: Siemens Healthineers does not accept agency resumes. Please do not forward resumes to our jobs alias, employees, or any other company location. Siemens Healthineers is not responsible for any fees related to unsolicited resumes.Salary Minimum: 224490Salary Maximum: 308671