Principal Software Engineer

Ladders

United States

Remote

USD 144,000 - 288,000

Full time

16 hours ago
Be an early applicant
Application generator

A complete application in a minute — tailored resume and cover letter, ready to send.

Get past ATS filters

Benefits offered by this job

Comprehensive health benefits
Paid time off
Retirement savings options
Wellness programs
Family well-being resources

Job summary

Ladders is seeking a Principal Software Engineer to join the team of a leader in the Healthcare space, shaping the technical direction for next-generation AI capabilities in a regulated environment.

You will lead the design of scalable services across cloud platforms, collaborate with Security and Legal, and deliver responsible AI systems while mentoring engineers and driving high-performance architectures.

Qualifications

  • 10+ years of IT experience across systems analysis, design, and engineering leadership.
  • 7+ years with microservices architectures and scalable APIs.
  • 5+ years leading large-scale, mission-critical applications with emphasis on security and performance.
  • 5+ years cloud delivery on AWS and/or Google Cloud.
  • 5+ years of DevOps and CI/CD automation.
  • 3+ years of Generative AI and LLMs development.

Responsibilities

  • Lead delivery of scalable AI services on AWS Bedrock and Google Cloud Vertex AI.
  • Architect and implement RAG solutions integrating diverse data sources.
  • Design multimodal input processing and secure service interfaces.
  • Define reference architectures for multi-cloud AI development.
  • Champion Responsible AI, including safety filters and compliance policies.
  • Collaborate with Security and Legal for HIPAA compliance.
  • Build observability frameworks and drive FinOps practices.
  • Mentor engineering teams to elevate coding standards and learning culture.
  • Monitor AI advancements and adapt platform strategy.

Skills

IT leadership
Microservices
Cloud architectures
DevOps/CI/CD
Generative AI/LLMs
Security/compliance
Stakeholder management

Job description

For our client, we are seeking a Principal Software Engineer to join the team of a leader in the Healthcare space.

This role will shape the technical direction for next-generation AI capabilities within a complex, regulated healthcare environment. You will lead the design of scalable services and reference architectures that support secure, high-performing solutions across cloud platforms. The position partners closely with Security, Legal, and engineering stakeholders to deliver responsible, compliant, and operationally sound AI systems.

Location: Remote - US based candidates only, no visa sponsorship available

Compensation: $144,200 - $288,400 annually

Responsibilities
  • Lead delivery of scalable AI services using AWS Bedrock and Google Cloud Vertex AI
  • Architect and implement RAG solutions integrating data from various sources
  • Design multimodal input processing solutions and secure service interfaces
  • Define reference architectures and standards for multi-cloud AI development
  • Champion Responsible AI practices, including safety filters and compliance policies
  • Collaborate with Security and Legal teams for HIPAA compliance
  • Build observability frameworks and drive FinOps practices
  • Mentor engineering teams to elevate coding standards and foster a learning culture
  • Monitor AI advancements and adapt platform strategy accordingly
Qualifications
  • 10+ years of hands-on IT experience across systems analysis, application design, and engineering leadership
  • 7+ years of experience with microservices architectures and scalable APIs
  • 7+ years managing stakeholder requirements for secure and performant technical solutions
  • 5+ years leading large-scale, mission-critical applications with an emphasis on security and performance
  • 5+ years of cloud initiative delivery on AWS and/or Google Cloud
  • 5+ years of DevOps and CI/CD automation expertise
  • 3+ years of software development focused on Generative AI and LLMs
Benefits
  • Comprehensive medical, dental, and vision coverage
  • Paid time off
  • Retirement savings options
  • Wellness programs
  • Additional resources for family well-being

Our client is an equal opportunity employer. We encourage you to apply even if you don’t meet every qualification - your background could be exactly what this team needs.

Get your free, confidential resume review.
or drag and drop your file here.
Similar jobs

Similar jobs worth comparing

Principal Software Engineer
Principal Software Engineer

CVS Health • Denver (CO)

On-site
USD 180,000 - 260,000
Medical coverage
Dental coverage
Vision coverage
+7
Senior Software Engineer - GenAI
Senior Software Engineer - GenAI

Prestige Staffing • Philadelphia

On-site
USD 100,000 - 140,000
Remote working flexibility
Professional growth opportunities
Influence over innovative AI solutions
Principal Full Stack Engineer (Remote)
Principal Full Stack Engineer (Remote)

Releady • Denver (CO)

Hybrid
Principal Software Architect New Mansfield, MA (Remote)
Principal Software Architect New Mansfield, MA (Remote)

eClinical Solutions LLC • Mansfield (MA), Northern (KY)

Hybrid
USD 168,000 - 210,000
Senior Staff Software Engineer, AI Developer Tools, Cloud Gemini Enterprise
Senior Staff Software Engineer, AI Developer Tools, Cloud Gemini Enterprise

Google • Seattle (WA)

On-site
USD 262,000 - 364,000
Health plan
401(k) with company match
Paid time off
+4
Principal Software Engineer (AI Platform & Full Stack Engineering) - Hybrid in MN
Principal Software Engineer (AI Platform & Full Stack Engineering) - Hybrid in MN

Optum • Minnetonka (MN)

Hybrid
USD 134,000 - 231,000
Comprehensive benefits package
Equity stock purchase
401(k) contribution
Principal Staff Software Engineer
Principal Staff Software Engineer

Harnham • Oakland (CA)

Hybrid
USD 400,000
Strong compensation
Meaningful equity
Opportunity to build from scratch
Senior Staff Software Engineer, AI Developer Tools, Cloud Gemini Enterprise
Senior Staff Software Engineer, AI Developer Tools, Cloud Gemini Enterprise

Google • Kirkland (WA)

On-site
USD 262,000 - 364,000
Health insurance
401(k) with company match
PTO 20 days/year
+4
Senior Staff Software Engineer, AI Developer Tools, Cloud Gemini Enterprise
Senior Staff Software Engineer, AI Developer Tools, Cloud Gemini Enterprise

Google • Sunnyvale (CA)

On-site
USD 262,000 - 364,000
Health insurance
Dental insurance
Vision insurance
+8
Principal Architect
Principal Architect

GeorgiaTEK Systems Inc. • United States

Remote
USD 120,000 - 160,000