Principal Scientist, Small Molecule Analytical Chemistry

Scorpion Therapeutics; Pennsylvania; On-site; USD 150,000 - 210,000; Full time

Job summary

Scorpion Therapeutics seeks a Principal Scientist to lead analytical characterization within drug product development and commercialization. You will oversee method development/validation, drug product testing, stability studies, and process characterization, while supporting scale-up/validation in a biopharma setting.

You will prepare regulatory CMC documentation, respond to inquiries, collaborate with cross-functional teams, and mentor scientists to build organizational capabilities at Rahway,

Qualifications

• PhD in analytical chemistry or related field with 7+ years (PhD) or 10+ years (MS) pharma experience.
• Extensive hands-on HPLC, UHPLC, GC, spectroscopy and validation experience.
• Proven regulatory documentation experience (IND, NDA, etc.).
• Strong problem-solving, communication and team leadership skills.
• Preferred: experience with LC/MS and troubleshooting of hyphenated techniques.

Responsibilities

• Oversee analytical method development/validation, drug product testing, stability studies and process characterization.
• Support scale-up/validation efforts and regulatory CMC submissions.
• Prepare regulatory CMC documentation and respond to inquiries.
• Collaborate with cross-functional teams and mentor scientists to grow organizational capabilities.

Skills

HPLC

UHPLC

GC

Spectroscopy

Validation

Leadership

Communication

Problem solving

LC/MS

Education

PhD in Analytical Chemistry or related

Tools

LC/MS

Job description

Principal Scientist

Leading analytical characterization in drug product development and commercialization within a biopharma setting.

Responsibilities

• oversee analytical method development/validation, drug product testing, stability studies, process characterization, and support scale-up/validation
• prepare regulatory CMC documentation and respond to inquiries
• collaborate with cross-functional teams
• mentor scientists and develop organizational capabilities

Requirements

• PhD in Analytical Chemistry or related, 7+ years (PhD) or 10+ years (MS) pharma experience
• extensive hands-on expertise with HPLC, UHPLC, GC, spectroscopy, and validation
• proven regulatory documentation experience (IND, NDA, etc.)
• strong problem-solving, communication, and team leadership skills
• Preferred: experience with hyphenated techniques like LC/MS and troubleshooting

High-Value

• small molecule pharma, late-stage development, cGMP environment, global regulatory submissions, cross-site collaboration, 10% travel

Location

Rahway, NJ and West Point, PA sites.