Principal Scientist - Precision Medicine

Regeneron Pharmaceuticals, Inc.; United States; Presencial; USD 129.000 - 210.000; Jornada completa

Descripción de la vacante

Regeneron Pharmaceuticals, Inc. seeks a Principal Scientist to lead precision medicine biomarker strategy for solid tumors, heme malignancies, and immune oncology.

This role focuses on designing experiments, guiding target mechanism insights, and informing patient stratification within clinical development. The successful candidate will spearhead cross-functional collaboration across Research, Clinical Development, and Diagnostics to deliver robust translational strategies and contribute to

Formación

• Ph.D., M.D., or MS with 4–7 years of cross-disciplinary pharmaceutical/biotech experience.
• Strong communication and presentation skills across cross-functional teams.
• Strategic understanding of biomarker technologies applied to translational or clinical research.

Responsabilidades

• Lead focused assay development and implementation for clinical trials.
• Coordinate data analysis with computational scientists integrating multi-omic data.
• Interpret results and communicate impact to guide clinical development strategy.
• Enable target identification, indication selection, early biomarker activity, and patient stratification.
• Partner across Research, Clinical Development, Clinical Pharmacology, Diagnostics, Biostatistics, and Clinical Operations.
• Manage internal and external research collaborations for translational assay development.
• Contribute to technical reports, study memos, clinical study reports, and publications.

Educación

Ph.D., M.D., or MS degree

Descripción del empleo

Principal Scientist, Precision Medicine (Biomarker) Strategy Lead

Precision Medicine

Build our future together:

The Precision Medicine department at Regeneron is responsible for designing and executing the overarching translational and clinical biomarker strategies for therapeutic candidates during clinical development. We are seeking to hire a Precision Medicine Strategy Lead at the Principal Scientist level focusing on solid tumor oncology, heme malignancies, and immune oncology.

In this highly matrixed role, the Principal Scientist will be responsible for defining the key scientific questions relating to the drug target mechanism of action, disease biology and prognostic biomarkers associated with disease heterogeneity and severity, as well as informing potential patient stratification or selection. This information will guide development of a robust Precision Medicine strategy.

When & where:

Location: Tarrytown, NY United States

Discover your role:

• Leading focused assay development and implementation of assays and associated sample collections throughout a clinical trial.
• Coordinating data analysis through collaboration with computational scientists involved in integrating multi-omic data: genomics, transcriptomics, and proteomics.
• Interpreting results and leading communication of the key impact of the data to guide decision making to inform the clinical development strategy.
• Enabling advances in target identification, indication selection, early indication of biological activity and patient stratification/selection.
• Partnering cross-functionally across Research, Clinical Development, Clinical Pharmacology, Companion Diagnostics, Biostatistics, and Clinical Operations to ensure seamless scientific alignment.
• Managing internal and external research collaborations to enable development of clinical fit for purpose assays and translational research.
• Contributing to technical reports, study memos, clinical study reports, and scientific publications.

This role requires:

• The ability to drive, manage, execute and deliver timely results for complex scientific projects.
• Strong communication and presentation skills.
• A strategic understanding of the application of biomarker technologies to basic, translational or clinical research.
• Demonstrated ability to effectively collaborate and work in cross-functional teams.
• A Ph.D., M.D., or MS and 4-7 years' experience participating effectively on cross-disciplinary teams in pharmaceutical or biotech.

We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)
$128,600.00 - $210,000.00