Principal Scientist, High-Throughput Biologics Automation

MSD; Boston (MA); On-site; USD 194,000 - 306,000; Full time

Job summary

Merck & Co. in USA (Massachusetts, Boston) is seeking a Principal Scientist to lead the High Throughput Production and Automation Group within Discovery Biologics.

The role directs molecular biology and protein production teams, and oversees automated solutions across the Boston Discovery Biologics organization. The candidate will design and implement automated, semi to fully automated high-throughput workflows, coordinating with discovery to advance therapeutics from bench to clinic.

Qualifications

• Ph.D. in Biochemistry, Computational Biology, Protein Engineering, Physics, Bioengineering, Molecular Biology, Chemistry, Pharmaceutical Science or related STEM field with 8+ years relevant industry experience, Master's with 12+ years relevant industry experience or Bachelor's with 14+ years of relevant industry experience in biochemistry or related field
• Relevant experience to include a record of increasing responsibility and independence in a similar industrial setting
• Experience supporting biologic therapeutic discovery programs

Responsibilities

• Provide scientific and strategic leadership to a team of 4 FTEs
• Lead continuous improvement of our physical and digital workflows as well as guiding future automated workflow expansion to continue delivering on tomorrow's therapeutic pipeline
• Manage outsourcing CROs for molecular biology and protein production to maximize the impact of our internal resources
• Effectively partner with teams within Discovery Biologics and across multidisciplinary interfaces to achieve organizational objectives
• Manage our fleet of liquid handlers (Dynamic Devices, TECAN, Hamilton) and associated peripheral equipment
• Leverage programmatic leadership experience to support and co‑lead Discovery Biologics therapeutic programs in collaboration with Therapeutic Areas
• Foster a culture of scientific excellence and collaboration by mentoring and developing scientists, leveraging individual strengths to build a high‑performing, engaged team
• Stay abreast of external advancements in relevant scientific fields and promote the external reputation of Discovery Biologics
• Be a champion for an inclusive culture

Skills

Antibody Discovery

Assay Development

Automation

Biologics

Expression Vectors

High-Throughput Screening

Molecular Biology Techniques

People Management

Protein Expression and Purification

Structural Biology

Therapeutic Proteins

Education

Ph.D. in Biochemistry/related STEM field with 8+ years’ experience

Tools

Dynamic Devices

TECAN

Hamilton

Job description

Merck & Co. in USA (Massachusetts, Boston) is seeking a Principal Scientist to lead the High Throughput Production and Automation Group within Discovery Biologics.

The role directs molecular biology and protein production teams, and oversees automated solutions across the Boston Discovery Biologics organization. The candidate will design and implement automated, semi to fully automated high-throughput workflows, coordinating with discovery to advance therapeutics from bench to clinic.