Principal Scientist, Drug Substance Process Development

BioSpace; North Chicago (IL); On-site; USD 140,000 - 190,000; Full time

Job summary

AbbVie is seeking a Principal Research Scientist I to drive late-stage development and commercialization of small molecule therapies. The role is based in North Chicago, IL, and requires leadership across multi-disciplinary teams including organic and analytical chemists, engineers, and quality science groups.

The candidate should have a strong track record in manufacturing process development, technology transfer, and regulatory documentation, with the ability to mentor teams and contribute to

Qualifications

• Experience in manufacturing process development and scale-up.
• Strong publication and patent history is advantageous.
• Ability to lead cross-functional process development teams.
• Excellent scientific communication and presentation skills.

Responsibilities

• Lead cross-functional project teams for manufacturing process development and tech transfer.
• Design and execute experiments to support program development and commercial manufacture.
• Set project strategies, define responsibilities and timelines.
• Act as SME for manufacturing processes and interact with multiple groups.

Skills

Inorganic chemistry

Process development

Scale-up

HPLC/UPLC/LC-MS/NMR

Scientific communication

Cross-functional leadership

GxP compliance

Education

Bachelor's degree or equivalent

Master's degree or equivalent

PhD in chemistry

Tools

HPLC

UPLC

LC-MS

NMR

Job description

AbbVie is seeking a Principal Research Scientist I to drive late-stage development and commercialization of small molecule therapies. The role is based in North Chicago, IL, and requires leadership across multi-disciplinary teams including organic and analytical chemists, engineers, and quality science groups.

The candidate should have a strong track record in manufacturing process development, technology transfer, and regulatory documentation, with the ability to mentor teams and contribute to