Principal Scientist I, Chemistry

AbbVie; North Chicago (IL); On-site; USD 125,000 - 237,000; Full time

Job summary

AbbVie in North Chicago, IL seeks a Principal Research Scientist I to lead late-stage development and commercialization of small molecule therapies from registration through lifecycle. The role spans across-functional teams in manufacturing development and scale-up, requiring a proven record in pharmaceutical manufacturing development.

You will design experiments, set project strategies, mentor teams, and author technical and regulatory documents while interfacing with chemistry, analytics, and

Qualifications

• Broad organic chemistry expertise with emphasis on manufacturing process development and scale-up.
• Strong scientific communication and presentation skills with track record of publications or patents.
• Demonstrated ability to lead cross-functional process development teams.

Responsibilities

• Lead cross-functional project teams for manufacturing process development and technology transfer.
• Design and execute laboratory experiments to support program development and commercial manufacture.
• Set project strategies, define responsibilities and timelines.
• Mentor/supervise a team and author technical/regulatory documents.

Skills

Strong communication

Leadership

Cross-functional collaboration

Education

Bachelor’s degree in chemistry

Master’s degree in chemistry

PhD in chemistry

Tools

HPLC

UPLC

LC-MS

NMR

Job description

• Compensation: USD 124500 - USD 236500 - yearly

Company Description

About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com . Follow @abbvie onLinkedIn, Facebook ,Instagram ,X andYouTube .

Job Description

AbbVieProduct Development Science & Technology (PDS&T)is seeking a Principal Research Scientist I to conductlate-stagedevelopmentand commercializationofsmall moleculetherapies, fromregistration through commercialization and the product lifecycle. We are seeking a highly motivated candidatewith a proven track record of accomplishment in the field ofpharmaceuticalmanufacturing development, to work in across-functional team environment at our North Chicago, IL location.

Key Responsibilities:

• The candidate willcontribute toand/or lead cross-functional project teams associated with manufacturing process development, process characterization/justification, transfer of technology to manufacturing sites, and support manufacturing activitiesforAbbVie’ssmall moleculepipeline.
• Design and executelaboratory experiments to supportprogram development and commercial manufacture.
• Set project strategies, defineproject responsibilities and timelines
• Provide leadership in a matrixed team setting, whileactingas an SME formanufacturingprocesses, interacting withvarious cross-functional groups and stakeholdersandcontributing to AbbVie’smanufacturing strategies.
• Author and reviewkeytechnicalandregulatory documents.
• The position involves multi-disciplinary interactions with organic chemists, analytical chemists, engineers, and solid-state scientists.
• The position also entails interfacing with many groups external toPDS&T, for example:Manufacturing Operations,RegulatoryAffairs, QualityAssurance, etc.

Responsibilities:

• Effectively functionas a principal investigator, generating original technical ideas and demonstrating creative 'out of the box' thinking to solve difficult problems and champion new technologies to achieve project goals.Make significant contributions to project team through lab-based activities. Independently responsible for project science withintheirarea of expertise on one or more project teams.
• Authorand/orreviewtechnical reports, manufacturing batch records andregulatory documents concerning Chemistry, Manufacturing and Control(CMC) subjects.Primary author of publications, presentations, and/or primary inventor of patents.
• Potential to mentor/supervise a team of one or moreindividuals, evaluate the performance ofthose individuals and be accountable for the effective performance of those individuals.
• Generate new scientific proposals and lead those efforts. Anticipate and critically evaluate scientific or regulatory advances or competitive threats and respond with appropriate new strategies.

Qualifications

• Bachelor’s Degree or equivalent education and typically 14+years of experience;master’s degreeor equivalent education and typically12+years of experience;PhD andtypically 6+ years of experienceinorganic chemistrywith a focus onmanufacturing process development and scale up. Candidates with less experience may be considered for other opportunities.
• A broad range of functional expertise in modern organic chemistry,mechanisticunderstanding, compound purification,control strategy developmentandstandard analytical methodology (e.g.,HPLC, UPLC, LC-MS, NMR).
• Demonstrated scientific communication and presentation skills.Experience and demonstrated success as an author of publications, presentations, and/or primary inventor of patents.
• Strong interpersonal and communication skills for facilitatingcollaborations and a demonstrated ability to lead cross-functional process development teams.
  
• Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
• Learns fast,understands key objectives,and can change course quicklyas needed.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation,and managesthe transition frominnovation toimplementation.
• Understands,adherestoand modelscorporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug compounds, and GxP compliance.

Additional Information

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.