Principal Scientist, Data Insights & Hypothesis Design

Tempus AI; New York (NY); On-site; USD 165,000 - 225,000; Full time

Job summary

Tempus AI is seeking a Principal Scientist to ensure scientific coherence of a multimodal data platform while bridging molecular science with scalable data engineering. You will lead data strategy, prototype data offerings, and guide cross-functional teams across oncology, neurology, and immunology domains.

The role emphasizes reproducible science, AI modeling, and translating analyses into production-grade data products with strong Python/R programming and data visualization skills.

Qualifications

• PhD in a quantitative, NGS-related discipline with 6+ years of industry experience.
• Deep expertise in oncology, neurology, or immunology and large-scale clinico-genomic dataset experience.
• Experience designing scalable data models and interfacing with data engineering teams.

Responsibilities

• Conduct data evaluations, write code (SQL, R, Python) and prototype data offerings.
• Translate client research objectives into clinico-genomic data strategies and data alignment.
• Serve as scientific authority, evaluate datasets, perform UAT, and build data insight reports.

Skills

Python

R

SQL

Education

PhD in quantitative biology/related field

Tools

SQL databases

Job description

Tempus AI is seeking a Principal Scientist to ensure scientific coherence of a multimodal data platform while bridging molecular science with scalable data engineering. You will lead data strategy, prototype data offerings, and guide cross-functional teams across oncology, neurology, and immunology domains.

The role emphasizes reproducible science, AI modeling, and translating analyses into production-grade data products with strong Python/R programming and data visualization skills.