Principal Scientist, Cardiovascular, Translational Development

Bristol-Myers Squibb; Princeton (NJ); On-site; USD 139,000 - 168,000; Full time

Benefits offered by this job

Comprehensive benefits

Flexible work options

Job summary

Bristol-Myers Squibb in Princeton, NJ seeks a Principal Scientist in Cardiovascular Translational Development to lead biomarker and translational strategy across late-stage programs. You will design program-specific biomarker plans, select assays, manage outsourcing, and ensure timely data delivery with CROs and internal teams.

You will provide scientific leadership, mentor colleagues, drive publications, support regulatory interactions, and collaborate across disciplines to advance the

Qualifications

• PhD with 4–8+ years translational medicine/clinical biomarker experience.
• 2+ years of early or late-stage clinical biomarker experience in biotech/pharma.
• Rigorous, detail-oriented scientist with leadership and organizational skills.

Responsibilities

• Designs and implements program-specific biomarker/translational plans.
• Manages clinical biomarker data delivery, analysis, and timelines with CROs.
• Prepares and delivers translational/biomarker presentations.
• Supports regulatory submissions and regulatory interactions as needed.

Skills

Translational biomarkers

Drug development

Communication skills

Project management

CRO collaboration

Leadership

Time management

Data interpretation

Education

PhD in relevant field

Job description

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.

Translational Development at BMS is part of the Global Research organization in BMS and leads late stage clinical, pharmacological and translational research and development activities for the pipeline and supports late stage portfolio for regulatory, translational development and life cycle management. Translational Development drives strategy across core therapeutic areas at BMS including hematology, oncology, immunology, cardiovascular and neuroscience. This group integrates laboratory science, clinical trial/biomarkers and asset development as well as disease research to maximize the potential of BMS current and future therapeutics. Incumbents with deep training and education in cardiovascular, or related disease areas, including but not limited to neurocardiac research.

Key Responsibilties

• Designs and implements program-specific development biomarker/translational plans
• Responsible for aiding in creation of clinical protocols, SAPs, SOWs, lab manual, and interfacing with CRO for execution of services, in conjunction with Biospecimen Operations and Procurement.
• Determines appropriate assays and vendors for clinical biomarkers, and manages outsourcing of biomarker assay development and validation partnering with Translational Sciences colleagues when applicable
• Manages clinical biomarker data delivery and analysis and associated timelines by working with relevant internal functions and CROs
• Prepares and delivers internal and external translational/biomarker presentations
• Maintains timelines for biomarker data related publication through interaction with Medical Communications and Publication team as needed
• Keeps up-to-date on relevant scientific/technical literature in order to applying external knowledge to internal research programs as appropriate and acts as a subject-matter expert within the team to critically evaluate the literature regarding the asset and disease biology
• Works with TM laboratory scientists and academic TLs to address nonclinical translational questions as needed
• Participates/leads post-hoc biomarker analysis and publication efforts
• Supports regulatory submissions and regulatory interactions as needed
• Participate in Diagnosis (PDx) biomarker assay development through collaboration with precision medicine group

Skills/Knowledge Required

• Expertise/knowledge in translational biomarkers in cardiovascular, or related disease areas.
• Experience in drug development and activities required for and related to clinical trial initiation, maintenance and completion
• Strong verbal and written communication skills
• Experience in interacting with CROs and TLs to manage projects and timelines
• Proven scientific/leadership expertise (working in teams, mentoring people, managing projects)
• Accountable for timelines and deliverables
• Prioritizes risks and implements contingency plans
• Experience in mining datasets, in collaboration with bioinformaticians to understand MoA, disease pathophysiology or establish patient segmentation hypotheses
• Communicates regularly; prepares and delivers presentations within the department, to governance and senior leadership bodies, and externally as requested
• Recognizes cross-functional issues and communicates within the larger organization.
• Provides translational guidance to multi-disciplinary teams and senior management.
• Has a track record of delivering results, driving continuous improvements, and building effective cross-functional networks.
• Ability to prioritize and manage time efficiently and support multiple projects in a fast pace and collaborative environment.
• Accurate and detailed record keeping, excellent organizational skills

Education/Experience

• Basic Qualifications: PhD with 4-8+ years of translational medicine/clinical biomarker experience
• 2+ years of early or late-stage clinical biomarker experience in biotech/pharma preferred Candidate must be a rigorous, detail-oriented scientist, with excellent leadership and organizational skills. Must be a flexible, results oriented, independent self-starter who enjoys working in a fastpaced dynamic matrix environment. #LI-Hybrid
• We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway.

Compensation Overview

• Brisbane - CA - US: $159,290 - $193,022
• Cambridge Crossing: $159,290 - $193,022
• Princeton - NJ - US: $138,520 - $167,849

The starting pay range(s) listed above is for full-time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully – carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance.

Benefits

Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability). U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year. Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays. Depending on eligibility, employees may also have access to additional time-off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs. Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day. U.S.-based job seekers can explore full benefit offerings at https://careers.bms.com/benefits

How We Work

Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations. If this posting is missing required information required by local law or incorrect, contact BMS at [e-mail] the Job Title and Requisition number. Do not send application-related inquiries to this email. To check your application status, please login to your Candidate Home Account.

R1600104 : Principal Scientist, Cardiovascular, Translational Development Data Privacy Link

We’re creating innovative medicines for patients fighting serious diseases. We’re also nurturing our own diverse team with inspiring work and challenging career options. No matter the role, each one of us makes a contribution. And that makes all the difference.