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An established industry player is seeking a Principal Research Scientist specializing in Peptide Chemistry to join their innovative team in North Chicago. This role focuses on leading the late-stage development and commercialization of peptides, requiring a deep understanding of organic chemistry and peptide synthesis. The ideal candidate will thrive in a collaborative environment, driving project strategies and authoring key regulatory documents. With a commitment to scientific excellence, this position offers the opportunity to make significant contributions to groundbreaking therapies that address serious health challenges. If you are passionate about advancing science and technology, this is the perfect opportunity for you.
Company Description
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.
Job Description
AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed in 2013, following separation from Abbott. AbbVie combines the focus and passion of a leading-edge biotech with the expertise and capabilities of a long-established pharmaceutical leader, to develop and market advanced therapies that address some of the world's most complex and serious diseases. AbbVie employs approximately 50,000 people worldwide and markets medicines in more than 170 countries. AbbVie Product Development Science & Technology (PDS&T) is seeking a Principal Research Scientist, Peptide Chemistry to conduct late-stage development and commercialization of Peptides, from registration through commercialization and the product lifecycle. We are seeking a highly motivated candidate with a proven track record of accomplishment in the field of peptide manufacturing development, to work in a multi-functional team environment at our North Chicago, IL location.
Key Responsibilities:
• The candidate will contribute to and/or lead cross-functional project teams associated with manufacturing process development, process characterization/justification, transfer of technology to manufacturing sites, and support manufacturing activities for peptides and potentially other modalities:
o Provide leadership in a matrixed team setting, while acting as an SME for peptide processes, interacting with various cross-functional groups and stakeholders and contributing to AbbVie's peptide manufacturing strategies.
o Set project strategies, define project responsibilities and timelines
o Author and review key regulatory documents, laboratory data, technical memos and reports.
• The position involves multi-disciplinary interactions with organic chemists, analytical chemists, engineers, and solid-state scientists.
• The position also entails interfacing with many groups external to PDS&T, for example: Manufacturing Operations, Regulatory Affairs, Quality Assurance, etc.
Responsibilities:
• Effectively functions as a principal investigator, generating original technical ideas and demonstrating creative 'out of the box' thinking to solve difficult problems and champion new technologies to achieve project goals. Make significant contributions to project team through lab-based activities. Independently responsible for project science within his/her area of expertise on one or more project teams.
Authors and/or reviews technical reports, manufacturing batch records and regulatory documents concerning Chemistry, Manufacturing and Control (CMC) subjects. Primary author of publications, presentations, and/or primary inventor of patents.
• Potential to mentor/supervise a team of one or more individuals, evaluate the performance of those individuals and be accountable for the effective performance of those individuals.
• Generate new scientific proposals and lead those efforts. Anticipate and critically evaluate scientific or regulatory advances or competitive threats and respond with appropriate new strategies.
Qualifications
• Bachelor's Degree or equivalent education and typically 14+ years of experience; master's degree or equivalent education and typically 12+ years of experience; PhD and typically 6+ years of experience in organic chemistry with a focus on peptide synthesis. Candidates with less experience may be considered for other opportunities.
• Experience in peptide process development and commercialization.
• A broad range of functional expertise in modern organic chemistry, mechanistic understanding, compound purification, control strategy development and standard analytical methodology (e.g., HPLC, UPLC, LC-MS, NMR).
• Demonstrated scientific communication and presentation skills. Experienced and demonstrated success as author of publications, presentations, and/or primary inventor of patents.
• Strong interpersonal and communication skills for facilitating collaborations and a demonstrated ability to lead cross-functional process development teams.
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: