Principal Research Scientist I

BioSpace; Worcester (MA); On-site; USD 121,000 - 230,000; Full time

Job summary

A leading company in the healthcare industry is seeking a Principal Research Scientist I to provide scientific leadership in immunogenicity and immunosafety assessments. The role involves mentoring junior staff and driving improvements in therapeutic assessments. Candidates should hold a Ph.D. with extensive experience in immunology and related fields.

Benefits

Comprehensive benefits package

401(k) and paid time off

Short-term and long-term incentive programs

Qualifications

• 6+ years experience with immunogenicity and immunosafety.
• Expertise in multicolor flow cytometry panel design.
• Extensive hands-on experience in cell-based assays.

Responsibilities

• Lead application of immunogenicity platforms to pipeline projects.
• Supervise junior scientists in immunogenicity assessments.
• Champion the design and coordination of in vitro studies.

Skills

Immunogenicity expertise

Cross-functional collaboration

Cell-based functional assays

Flow cytometry

Project management

Education

Ph.D. in Biological Sciences

Master's in Biological Sciences

Bachelor's in Biological Sciences

Tools

BD LSRFortessa

BD FACSDive

FlowJo software

Job description

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Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onX,Facebook,Instagram,YouTube,LinkedInandTik Tok.

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onX,Facebook,Instagram,YouTube,LinkedInandTik Tok.

Job Description

The candidate will apply their immunosafety and immunogenicity expertise to provide scientific and technical leadership in a cross-functional team assessing and implementing an immunogenicity platform with in silico and in vitro strategies, while playing a crucial role as an immunosafety lead advising teams in the development of preclinical molecules for multiple projects. The candidate is also expected to mentor junior immunosafety team members, foster productive collaborations, and demonstrate effective communication within scientific teams.

Responsibilities

• Lead integration and application of in silico and in vitro immunogenicity platforms to AbbVies pipeline.
• Supervise junior scientists providing scientific and technical leadership in the design and execution of in vitro immunogenicity and immunosafety assessments to support the de-risking of novel therapeutic candidates.
• Encourage ideas, drive continuous improvements, and support initiatives to enhance immunogenicity and immunosafety risk assessments of novel therapeutics.
• Represent the In Vitro Immunosafety team in cross-functional project team meetings championing the design and coordination of in vitro immunogenicity and immunosafety studies.
• Author publication, presentations, and/or regulatory documents.
  
  
  

Qualifications

• Ph.D. in Biological Sciences, Cellular Immunology, or related field with 6+ years of related experience OR Master Degree in Biological Sciences, Cellular Immunology, or related field with 12+ years of related experience, OR Bachelor Degree inBiological Sciences, Cellular Immunology, or related field with 14+ years of related experience.
• Extensive experience with in silico immunogenicity prediction evaluations and in vitro immunogenicity assay development and implementation.
• Deep understanding of innate and adaptive cellular immunology with strong hands-on experience in cell-based functional assays and immune cell phenotyping.
• Extensive experience with multicolor flow cytometry panel design, BD LSRFortessa instrument operation, BD FACSDive and FlowJo software, and flow cytometry data analysis.
• Proven track record of cross-functional collaborations and project management yielding productive outcomes.
• Excellent interpersonal and oral/written communication skills.
• Results-oriented work ethic and a positive "can-do" attitude with a strong sense of urgency and self-motivated desire to achieve common business goals.
• Demonstrated ability to collaborate effectively in a dynamic, cross-functional matrix environment.
  
  
  

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
• This job is eligible to participate in our short-term incentiveprograms.
• This job is eligible to participate in our long-term incentiveprograms
  
  
  

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

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