Principal Research Scientist I

BioSpace; North Chicago (IL); On-site; USD 180,000 - 240,000; Full time

Job summary

AbbVie is seeking a highly motivated toxicologist to support discovery-stage programs across therapeutic areas within preclinical safety. The role involves designing and executing safety assessment strategies using in silico, in vitro, and in vivo tools to advance pipeline programs.

The candidate will work cross-functionally, provide subject matter expertise, and may mentor a team. Strong communication and literature integration are essential to drive data-driven decisions.

Qualifications

• Experience directing the use of, and interpreting data from, in vitro safety studies.
• Demonstrated ability to operate independently and develop strategies.
• Thorough theoretical and practical understanding of toxicology.

Responsibilities

• Design and execute safety strategies for discovery-stage programs across therapeutic areas.
• Develop and deploy in vitro safety tools and NAMs with relevant endpoints.
• Mentor/supervise a team and collaborate cross-functionally to advance programs.
• Communicate with leadership to align program strategy and progress.
• Stay current with literature and integrate it into safety assessments.

Skills

Independent work

Scientific communication

Cross-functional collaboration

Data interpretation

Leadership (potential)

Education

Bachelor degree or equivalent + 14+ years

Master’s degree + 12 years

PhD + 6+ years

Job description

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

Job Description

Purpose

We are seeking a highly-motivated toxicologist to support discovery-stage programs across therapeutic areas within preclinical safety. As part of the Investigative Toxicology and Pathology group, the successful candidate will effectively leverage in silico, in vitro, and in vivo tools to design and execute a safety assessment strategy to support pipeline advancement. As project toxicologist, this scientist will work cross-functionally, providing critical subject matter expertise and data integration to drive progress for programs.

Responsibilities

• Support project teams to design and execute a safety strategy specific to the needs of the project by leveraging internal and external resources, in silico tools, in vitro models, and in vivo studies.
• Support development and deployment of in vitro tools for safety assessment (simple and complex in vitro models, or NAMs) and utilize appropriate endpoints (imaging, toxicogenomic, etc) to support decision-making.
• Demonstrate the ability to identify and resolve key project hurdles by effectively utilizing available information and resources.
• Communicate effectively across cross-functional teams and with leadership to support alignment on program strategy.
• Proactively seek out new information in the literature and incorporate this into individual projects as well as the overall safety assessment strategy.
• Seize opportunities to pursue project-relevant exploration and experiments to support data-driven decision-making and program progress.
• May mentor/supervise a team of one or more and evaluate the performance of those individuals; accountable for the effective performance of the team/individuals.
• Collaborate effectively with other teams to identify areas of scientific advancement and efficiency.

Qualifications

Required

• Bachelor’s Degree or equivalent education and extensive, typically 14+ years of experience, Master’s Degree or equivalent education and typically 12 years of experience, PhD and typically 6+ years of experience.
• Experience directing the use of, and interpreting data from, in vitro safety studies.
• Demonstrate ability to function independently, generating original research or development strategies.
• Possess thorough theoretical and practical understanding of own scientific discipline.
• Effective writer and communicator of research. Demonstrated scientific communication and presentation skills.

Preferred

• People leadership and management experience
• DABT board certification or equivalent
• Experience working on cross-functional project teams, including but not limited to, within pharmaceutical development

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company’s sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html