Principal Research Scientist I

Allergan; Chicago, Northern (IL, KY); On-site; USD 110,000 - 160,000; Full time

Benefits offered by this job

Paid time off

Medical/dental/vision insurance

401(k) plan

Long-term incentive programs

Job summary

AbbVie is seeking a highly motivated toxicologist to support discovery-stage safety programs across therapeutic areas. You will leverage in silico, in vitro, and in vivo tools to design and execute a safety assessment strategy, working cross-functionally to drive program progress.

The role requires strong independent work, expertise in safety studies, and clear communication with teams and leadership. A focus on data-driven decision-making will be essential to advancing pipelines.

Qualifications

• PhD in toxicology or a related field
• Experience directing in vitro safety studies
• Ability to function independently and generate research or development strategies
• Thorough theoretical and practical understanding of toxicology
• Effective scientific writing and communication skills

Responsibilities

• Design and execute a safety strategy for discovery-stage programs using in silico, in vitro, and in vivo approaches
• Develop and deploy in vitro tools for safety assessment and select appropriate endpoints to support decision-making
• Identify and resolve project hurdles using available data and resources
• Communicate progress and alignment of program strategy across cross-functional teams and leadership
• Pursue data-driven exploration to advance programs

Job description

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

Job Description

Purpose

We areseekingahighly-motivatedtoxicologist to supportdiscovery-stage programs across therapeutic areas within preclinical safety. As part of the Investigative Toxicology and Pathology group,the successful candidate will effectivelyleveragein silico, in vitro, and in vivo tools to design and execute a safety assessment strategy to support pipeline advancement.Asprojecttoxicologist, this scientist will work cross-functionally, providing critical subject matterexpertiseand data integration to drive progress for programs.

Responsibilities

• Support project teamsto design and execute a safety strategy specific to the needs of the projectbyleveraginginternal and external resources, in silico tools, in vitro models, and in vivo studies. Select and design experiments that answer key questions, are decision-enabling, andpromote judicious progression of programs.
• Support development and deployment ofin vitro tools for safety assessment (simple and complex in vitro models, or NAMs) andutilizeappropriate endpoints(imaging,toxicogenomic,etc) to support decision‑making.
• Demonstrate the ability toidentifyandresolve key project hurdles by effectivelyutilizingavailable information andresources.
• Communicate effectively across cross‑functional teams andwithleadership to support alignment on program strategy.
• Proactively seek outnew informationin the literature and incorporate this into individual projects as well as the overallsafety assessment strategy.
• Seize opportunities to pursue project‑relevantexploration and experiments to support data‑driven decision‑making and program progress.
• May mentor/supervise a team of one ormoreand evaluate the performance of thoseindividuals;accountable for the effective performance of the team/individuals.
• Collaborate effectively with other teams toidentifyareas of scientific advancement and efficiency.

Qualifications

Required:

• Bachelor’s Degree or equivalent education andextensive,typically 14+years of experience,Master’s Degreeor equivalent education and typically 12years of experience, PhD and typically6+years of experience.
• Experience directing the use of,and interpreting data from,in vitro safety studies.
• Demonstrateabilityto function independently, generating original research or development strategies.
• Possess thorough theoretical and practical understanding ofownscientific discipline.
• Effective writer and communicator of research.Demonstrated scientific communication and presentation skills.

Preferred:

• People leadership and management experience
• DABT board certification or equivalent
• Experienceworking on cross‑functional project teams, including but not limited to, within pharmaceutical development

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
• This job is eligible toparticipatein our long-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company's sole andabsolutediscretion unless and until paid andmay bemodifiedat the Company’s sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html