Principal Research Scientist I

BioSpace

North Chicago (IL)

On-site

USD 120,000 - 180,000

Full time

21 hours ago
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Benefits offered by this job

Paid time off
Health, dental, vision insurance
401(k) plan

Job summary

AbbVie is seeking a highly motivated toxicologist to support discovery-stage programs across therapeutic areas within preclinical safety. As part of the Investigative Toxicology and Pathology group, you will design and execute a safety assessment strategy to support pipeline advancement, leveraging in silico, in vitro, and in vivo tools to drive program progress.

The role requires strong independent research capabilities, deep scientific expertise, and effective communication with

Qualifications

  • Experience directing the use of, and interpreting data from, in vitro safety studies.
  • Demonstrated ability to function independently, generating original research or development strategies.
  • Thorough theoretical and practical understanding of the scientific discipline.
  • Strong written and oral communication of scientific research.

Responsibilities

  • Design and execute a safety strategy for discovery-stage programs using in silico, in vitro, and in vivo tools.
  • Develop and deploy in vitro tools for safety assessment and use appropriate endpoints to support decisions.
  • Identify and resolve project hurdles using available information and resources.
  • Communicate across cross-functional teams and leadership to align on program strategy.
  • Incorporate current literature into safety assessment strategies and projects.
  • Pursue project-relevant exploration and experiments to support data-driven decisions.
  • Mentor or supervise team members and evaluate performance where applicable.
  • Collaborate with other teams to identify areas for scientific advancement and efficiency.

Skills

In vitro safety studies
Independent researcher
Scientific discipline expertise
Scientific communication

Education

Bachelor's degree or equivalent
Master's degree or equivalent
PhD with 6+ years experience

Job description

Company Description
About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.

Job Description
Purpose

We areseekingahighly-motivatedtoxicologist to supportdiscovery-stage programs across therapeutic areas within preclinical safety. As part of the Investigative Toxicology and Pathology group,the successful candidate will effectivelyleveragein silico, in vitro, and in vivo tools to design and execute a safety assessment strategy to support pipeline advancement.Asprojecttoxicologist, this scientist will work cross-functionally, providing critical subject matterexpertiseand data integration to drive progress for programs.

Responsibilities
  • Support project teamsto design and execute a safety strategy specific to the needs of the projectbyleveraginginternal and external resources, in silico tools, in vitro models, and in vivo studies. Select and design experiments that answer key questions, are decision-enabling, andpromote judicious progression of programs.
  • Support development and deployment ofin vitro tools for safety assessment (simple and complex in vitro models, or NAMs) andutilizeappropriate endpoints(imaging,toxicogenomic,etc) to support decision-making.
  • Demonstrate the ability toidentifyandresolve key project hurdles by effectivelyutilizingavailable information andresources.
  • Communicate effectively across cross-functional teams andwithleadership to support alignment on program strategy.
  • Proactively seek outnew informationin the literature and incorporate this into individual projects as well as the overallsafety assessment strategy.
  • Seize opportunities to pursue project-relevantexploration and experiments to support data-driven decision-making and program progress.
  • May mentor/supervise a team of one ormoreand evaluate the performance of thoseindividuals;accountable for the effective performance of the team/individuals.
  • Collaborate effectively with other teams toidentifyareas of scientific advancement and efficiency.
Qualifications
Required
  • Bachelors Degree or equivalent education andextensive,typically 14+years of experience,Masters Degreeor equivalent education and typically 12years of experience, PhD and typically6+years of experience.
  • Experience directing the use of,and interpreting data from,in vitro safety studies.
  • Demonstrateabilityto function independently, generating original research or development strategies.
  • Possess thorough theoretical and practical understanding ofownscientific discipline.
  • Effective writer and communicator of research.Demonstrated scientific communication and presentation skills.
Preferred
  • People leadership and management experience
  • DABT board certification or equivalent
  • Experienceworking on cross-functional project teams, including but not limited to, within pharmaceutical development
Additional Information
  • The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.
  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
  • This job is eligible toparticipatein our long-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company's sole andabsolutediscretion unless and until paid andmay bemodifiedat the Companys sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

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