Principal Medicinal Chemist - Drug Discovery Leader

1001 Amgen Inc.; South San Francisco (CA); On-site; USD 165,000 - 224,000; Full time

Benefits offered by this job

Flexible work models

Remote/hybrid opportunities

Competitive benefits

Job summary

Amgen Inc. in South San Francisco seeks a Principal Scientist in Medicinal Chemistry to design, synthesize, and purify novel compounds for potential clinical development. This onsite role participates in Amgen’s IPP PROTAC initiatives and advances targets through innovative chemistry and collaboration.

The role involves leading medicinal chemistry teams, publishing results, and mentoring researchers, with a competitive salary and a strong emphasis on collaboration and scientific impact.

Qualifications

• PhD with multiple years of scientific experience or equivalent combination toward drug discovery.
• Strong background in organic synthesis, medicinal chemistry, and related disciplines.
• Proven ability to lead medicinal chemistry projects and deliver clinical candidates.

Responsibilities

• Devise and implement state-of-the-art scientific research through laboratory experiments and project planning with timelines and milestones.
• Review, analyze, and interpret data; regularly update and document results; collaborate with scientists and stay current with literature and technology development.
• Advise supervisors and colleagues, participate in meetings, contribute to publications/patents, and mentor research staff.

Skills

Organic synthesis

Medicinal chemistry

Team leadership

Communication

Education

Doctorate degree in Chemistry

Master's degree

Bachelor's degree

Job description

Amgen Inc. in South San Francisco seeks a Principal Scientist in Medicinal Chemistry to design, synthesize, and purify novel compounds for potential clinical development. This onsite role participates in Amgen’s IPP PROTAC initiatives and advances targets through innovative chemistry and collaboration.

The role involves leading medicinal chemistry teams, publishing results, and mentoring researchers, with a competitive salary and a strong emphasis on collaboration and scientific impact.