Principal Materials Scientist, Drug Formulation & QbD

Vertex Pharmaceuticals; Boston (MA); On-site; USD 120,347,000 - 131,809,000; Full time

Job summary

Vertex Pharmaceuticals in Boston, MA, is seeking a Materials Science Principal to advance drug candidates from early development through commercial lines using Quality by Design (QbD) principles. The role blends lab-based and computational tools to connect material properties with pharmaceutical processing.

You will design experiments, perform characterization, analyze data with statistics, and maintain rigorous notebooks.

Qualifications

• Master's degree in chemical or materials engineering or related field.
• Bachelor's degree in a related physical science with 5+ years of experience.

Responsibilities

• Perform advanced characterization and develop predictive models linking material properties to processing conditions.
• Design and execute laboratory experiments for drug characterization and solid dosage development.
• Interpret data with basic statistical analysis and document results clearly.
• Maintain accurate laboratory notebooks, protocols, results, and observations.

Skills

Statistical analysis

Team collaboration

Quality by Design

Materials science

Education

Master's degree in chemical or materials engineering

Bachelor's degree in physical science

Tools

Laboratory equipment

Computational tools

Job description

Vertex Pharmaceuticals in Boston, MA, is seeking a Materials Science Principal to advance drug candidates from early development through commercial lines using Quality by Design (QbD) principles. The role blends lab-based and computational tools to connect material properties with pharmaceutical processing.

You will design experiments, perform characterization, analyze data with statistics, and maintain rigorous notebooks.