Principal Clinical Scientist

Alignerr Corp.; Charlotte (AR); Remote; USD 83,000 - 165,000; Part time

Job summary

Alignerr seeks a Principal Clinical Scientist (AI Training) to bring senior-level rigor to regulator-ready AI data for real-world medical evidence. You will design trial protocols and audit results to ensure scientific soundness and compliance with FDA/EMA expectations, while shaping how AI systems reason about clinical endpoints and outcomes.

The role is remote, hourly, and freelance with 10–40 hours per week, offering flexible scheduling for experts who want impactful work at the intersection

Qualifications

• Senior-level experience designing protocols for regulatory submission.
• Experience interpreting clinical data for FDA/EMA or equivalents.
• Strong grounding in biostatistics or translational science.
• Detail-oriented with evidence-driven evaluation.

Responsibilities

• Design and review clinical trial protocols for regulator-ready datasets.
• Interpret and audit clinical trial results for regulatory alignment.
• Evaluate AI-generated clinical analyses for rigor.
• Provide structured feedback to improve AI model reasoning about trial data.

Skills

Trial design

Regulatory interpretation

Biostatistics

Clinical research methods

Job description

Principal Clinical Scientist (AI Training)

About The Role

What if your deep expertise in clinical trial design and regulatory science could directly influence how AI understands and evaluates real-world medical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor to frontier AI research — helping ensure that the clinical intelligence built into next-generation AI systems meets the standards expected in real regulatory submissions.

This is a fully remote, flexible contract role designed for experienced clinical scientists who want to do meaningful work at the intersection of medicine and AI — on their own schedule.

• Organization: Alignerr
• Type: Hourly Contract
• Location: Remote
• Commitment: 10–40 hours/week

What You'll Do

• Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluation
• Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory expectations
• Evaluate AI-generated clinical analyses for scientific soundness and methodological rigor
• Provide expert, structured feedback that directly improves how AI models reason about clinical trial data, endpoints, and outcomes
• Work independently and asynchronously — fully on your own schedule

Who You Are

• Senior-level experience designing clinical trial protocols intended for regulatory submission
• Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent international bodies
• Strong grounding in clinical research methodology, biostatistics, or translational science
• Naturally detail-oriented with a systematic, evidence-driven approach to evaluation
• Clear and precise written communicator — able to articulate complex scientific reasoning in structured feedback

Nice to Have

• Prior experience with data annotation, data quality assurance, or evaluation systems
• Familiarity with AI tools or clinical informatics platforms
• Background in pharmacology, oncology, rare disease, or another specialist therapeutic area
• Experience contributing to regulatory dossiers, CTD submissions, or scientific advisory processes

Why Join Us

• Work directly on frontier AI systems impacting clinical and biomedical research at a global scale
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure of meaningful, task-based expert work
• Influence how AI understands, evaluates, and reasons about real-world clinical evidence
• Collaborate with world-leading AI research teams and labs
• Potential for ongoing work and contract extension as new projects launch