Principal Biostatistician – Clinical Trials & Analytics

Cytel; Santa Fe (NM); On-site; USD 140,000 - 210,000; Full time

Job summary

Cytel is seeking an experienced Principal Biostatistician to lead one or more Phase I–IV clinical studies within a client-embedded setting. You will develop integrated analytic plans, employ machine learning and traditional methods, and oversee work across vendors as needed.

Key duties include study design, SAP development, efficacy analyses, and regulatory-facing summaries, with emphasis on collaboration, communication, and adaptive prioritization in a dynamic environment.

Qualifications

• Master's degree in Statistics or Biostatistics or related field.

Responsibilities

• Participate in study protocol development and design discussions.
• Conduct exploratory analyses to inform decision-making.
• Apply advanced statistical methods for efficacy and longitudinal analyses.
• Design and run simulation studies to evaluate design and methods.
• Lead efficacy analyses and interpret primary and secondary endpoints.
• Review CRFs and develop Statistical Analysis Plans (SAPs).
• Perform statistical analyses and interpret results.
• Provide strategic statistical guidance to cross-functional teams.
• Communicate statistical methodologies clearly to non-technical stakeholders.
• Collaborate effectively to meet project timelines.
• Demonstrate adaptability as priorities change.

Skills

R programming

SAS programming

Clinical trial statistics

Cross-functional leadership

Study lead experience

Education

Master's in Statistics/Biostatistics

PhD preferred

Tools

R

SAS

Job description

Cytel is seeking an experienced Principal Biostatistician to lead one or more Phase I–IV clinical studies within a client-embedded setting. You will develop integrated analytic plans, employ machine learning and traditional methods, and oversee work across vendors as needed.

Key duties include study design, SAP development, efficacy analyses, and regulatory-facing summaries, with emphasis on collaboration, communication, and adaptive prioritization in a dynamic environment.