Principal Biologics Analytics Scientist I

AbbVie Inc.; North Chicago (IL); On-site; USD 125,000 - 237,000; Full time

Benefits offered by this job

Paid time off

Health/dental/vision insurance

401(k)

Job summary

AbbVie Biologics Analytical R&D is hiring a Principal Research Scientist I to lead phase-appropriate analytical development strategies for complex biologics characterization, including ADCs and multi-specific molecules. You will design extended characterization methods to enable in-process analytics and stability studies, while contributing to cross-functional teams with data-driven insights.

The role requires strong hands-on MS expertise, familiarity with SEC/HIC/HILIC/RPLC/IEX/CE/icIEF, plus

Qualifications

• BS or higher with many years of industry experience in analytical chemistry or biochemistry.
• PhD with extensive biologics characterization experience preferred.
• Proficiency in mass spectrometry-based characterization of biologics and related data analysis.
• Familiarity with separation-based analytical techniques (SEC, HIC, HILIC, RPLC, IEX, CE, icIEF).
• Knowledge of analytical CMC, method validation, CGAs, comparability studies.

Responsibilities

• Lead phase-appropriate analytical development strategies for biologics characterization (ADC, PDC, AOC, fusion proteins, multi-specific antibodies, etc.).
• Design and build out extended characterization methods for in-process analytics, release, stability, and comparability studies.
• Provide cross-functional collaboration and data-driven contributions to programs; deliver results.
• Represent the function in project teams with technical oversight.
• Author and review analytical sections for regulatory filings and publications; participate in external presentations.

Skills

Mass spectrometry

Biologics characterization

MS data analysis

Analytical method development

Chromatography

Lab automation

Regulatory writing

Education

BS or equivalent

MS or equivalent

PhD in Analytical Chemistry/Biochemistry/Biology

Tools

Mass spectrometry software

Regulatory documentation tools

Job description

AbbVie Biologics Analytical R&D is hiring a Principal Research Scientist I to lead phase-appropriate analytical development strategies for complex biologics characterization, including ADCs and multi-specific molecules. You will design extended characterization methods to enable in-process analytics and stability studies, while contributing to cross-functional teams with data-driven insights.

The role requires strong hands-on MS expertise, familiarity with SEC/HIC/HILIC/RPLC/IEX/CE/icIEF, plus