Principal Automation Engineer, Bio-Assay

Merck KGaA, Darmstadt, Germany; Billerica (MA); On-site; USD 100,000 - 140,000; Full time

Job summary

A leading company in the pharmaceutical industry seeks a Principal Automation Engineer to enhance bioassay efficiency through automation solutions. The role involves developing and validating analytical methods, training staff, and collaborating across teams. Ideal candidates will have extensive experience in bioassays and automation, contributing to innovative healthcare solutions.

Qualifications

• 7+ years experience in bioassays and functional characterization methods.
• Hands-on experience with developing assays for biological activities.
• Experience with viral infectivity assays is a plus.

Responsibilities

• Implement automated solutions to increase efficiency for bioassays.
• Execute the development and validation of analytical methods.
• Train staff and maintain laboratory consistency.

Skills

Bioassays

Automation

Robotics

Cellular Biology

Biotechnology

Education

Bachelor’s Degree in Cellular Biology

Master’s Degree

PhD in Cellular Biology

Tools

ELISA

PCR

qPCR

ddPCR

Sequencing

Job description

Principal Automation Engineer, Bio-Assay

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Principal Automation Engineer, Bio-Assay

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Work Your Magic with us! Start your next chapter and join EMD Serono.

Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

Principal Automation Engineer, Bio-Assay

Your Role

As a member of the in AIDD team group, you will be responsible for implementing automated solutions such as liquid handlers and other automation devices to increase efficiency and throughput for bioassays (biologics assays and immunoassays). You will be responsible for onboarding and validating assays onto HT automated platforms. You will be responsible for maintaining the devices in an operable state and training others on how to use them. The Scientist is also responsible for supporting the development, qualification, transfer, and validation of analytical methods for the analysis and characterization of biologics entities.

You Will Be Responsible To

• Execute the development and validation of analytical methods for the analysis and characterization of biopharmaceuticals onto a high throughput automated platform.
• Create written procedures and protocols. Transfer, qualify or validate methods as needed.
• Bioassay development and product characterization assays, support stability and in-process testing of a wide range of bio therapeutic modalities, including: Viral vectors, monoclonal antibodies (mAbs), ADCs, bi-specifics, cell & gene therapy, and other biologic
• Actively participate on cross-functional teams within Biologics Development and provide support to external departments. Openly share scientific expertise and collaboratively help the team to formulate rational solutions to problems.
• Develop protocols and SOPs, train staff and maintain the laboratory consistent with departmental and company requirements. Understand, document, and adjust Quality Systems to match the project stage (e.g. pre-development or development).
• Maintain a good and current knowledge of the scientific and technical literature pertinent to the project and necessary for development of state-of-the-art analytical methods, including the acquisition of necessary equipment.
  
  

Location: Billerica, MA

Travel: <10%

Who You Are

Minimum Qualifications:

• Bachelor’s Degree in Cellular Biology, Cellular Bio-Chemistry, Biotechnology, Computer Science, Automation, Robotics or related technical field; or equivalent education with at least 7 years of experience, or Master’s Degree with at least 5 years of experience.
• Hands-on experience with bioassays and functional characterization methods for monoclonal antibodies, ADCs, Bi-Specifics, various viral vectors specific titer assays & neutralization assays.
• Hands-on experience with developing assays to measure various biological activities, including antigen/receptor binding, alteration of intracellular signaling, induction of cell death, and Fc effector functions
• Experience with viral infectivity assays and cell and gene therapy products is a plus
• Good understanding of various bio & molecular techniques such as ELISA, PCR, qPCR, ddPCR, Sequencing, etc.,
• In depth knowledge and experience with bioassay development, optimization, technology transfer, assay qualification and validation following ICH guidelines
  
  

Preferred Qualifications

• PhD in Cellular Biology, Cellular Bio-Chemistry, Biotechnology, Computer Science, Automation, Robotics or related fields
• Strong experience in implementing automated Bio-Assay processes, including the use of robotic systems.
• Detailed knowledge of scheduling software design and integration across an automated laboratory environment.
• Experience with automation project development from concept, preliminary and final design, through construction, installation and project closure.
• Comfortable working in an entrepreneurial environment, agile and face-paced teams
• Self-driven, results-oriented leader with proven collaborative working style
  
  

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research and Science

• Industries

  Pharmaceutical Manufacturing

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