Principal Analytical Scientist (Automation)

BioSpace; Town of East Greenbush (NY); Vor Ort; USD 92.000 - 151.000; Vollzeit

Benefits dieser Stelle

Annual bonuses

Equity awards

Pension or retirement benefits

401(k) company match

Health and wellness programs

Zusammenfassung

Regeneron is seeking a Principal Analytical Scientist to join our Quality Control team in Rensselaer, NY, onsite. You will design, develop, and scale automated assay workflows across mass spectrometry, chromatography, bioassays, and ELISA, while mentoring scientists and advancing automation.

You will lead method optimization, transfer workflows to QC partners, and collaborate with vendors. Strong programming in Python, R, or VBA and hands-on automation experience are essential.

Qualifikationen

• 8+ years of industry experience in analytical development, automated automation, and QC lifecycle management.
• Hands-on expertise with automated liquid handling platforms and related software.
• Proficiency in scripting languages (Python, R, VBA) for data analysis and workflow automation.
• Deep knowledge of QC analytics including MS, chromatography, electrophoresis, bioassay, or ELISA.
• Ability to design studies, work independently, and drive projects.
• Level will be determined based on qualifications at offer.

Aufgaben

• Lead design, implementation, and optimization of automated assay workflows across modern laboratory platforms.
• Mentor and develop junior scientists to build automation capability.
• Set priorities, coordinate work, and track progress against milestones.
• Design and execute studies to evaluate emerging automation technologies.
• Lead investigations into automated method performance and drive improvements.
• Transfer workflows to QC and partner functions with training and transfer plans.
• Collaborate with vendors to evaluate new technologies for QC.
• Prepare reports, SOPs, and automation documentation; communicate risks and findings.

Kenntnisse

Mass spectrometry

Chromatography

Bioassay

Electrophoresis

ELISA

Scripting (Python/R/VBA)

Automated liquid handling

Vendor collaboration

Ausbildung

PhD in Chemistry/Biochemistry/Biology

Tools

Cellario

Venus (Hamilton)

OneLab (Andrew+)

Jobbeschreibung

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Principal Analytical Scientist to join our Quality Control team in Rensselaer, NY, supporting our IOPS organization on-site. In this role, you will shape the future of QC analytical testing by designing, developing, and scaling automated assay workflows across advanced laboratory platforms, while mentoring scientists and fostering a culture of technical growth and innovation. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & where

Location: Rensselaer, NY (Tempel Lane)

Work Shift: Monday-Friday 1st shift

Discover Your Role

• Lead the design, implementation, and optimization of automated assay workflows across modern laboratory platforms, applying deep expertise in mass spectrometry, chromatography, bioassay, electrophoresis, and ELISA.
• Mentor and develop junior and mid-level scientists, building team capability in analytical science and laboratory automation.
• Set priorities, coordinate work, and track progress on analytical and automation initiatives against key milestones.
• Independently design and execute studies to evaluate emerging automation technologies and troubleshoot existing systems with limited supervision.
• Lead complex investigations into automated method performance, supporting verification activities and driving continuous improvement.
• Transfer automated workflows to QC and partner functions by developing training materials, transfer plans, and acceptance criteria.
• Engage cross-functional collaborators and equipment vendors to evaluate new technologies and assess their fit for QC applications.
• Prepare clear scientific reports, automation procedures, and SOPs; communicate findings, risks, and mitigation strategies to management and cross-functional teams.
• Bring hands‑on experience programming and optimizing automated liquid handling systems (e.g., Hamilton/Venus, Andrew+/OneLab, or Cellario) and scripting in Python, R, or VBA.
• Apply strong troubleshooting skills across both analytical methods and automated instrumentation to resolve complex technical challenges.
• Make sound, independent decisions and proactively recommend experiments or solutions based on deep expertise in analytical science and automation.

This Role Requires

• 8+ years of industry experience in analytical development, laboratory automation, and QC method lifecycle management (or equivalent combination of education and experience).
• Demonstrated hands‑on expertise in automated liquid handling platforms and associated software programming.
• Proficiency in scripting languages (Python, R, or VBA) for data analysis, workflow automation, or system integration.
• Deep knowledge of QC analytical techniques including mass spectrometry, chromatography, electrophoresis, bioassay, or ELISA.
• Proven ability to work independently, design scientifically sound studies from broad objectives, and drive projects to completion.
• Level will be determined based on qualifications at the time of offer.

Preferred

• PhD in Chemistry, Biochemistry, Biology, or a related field.
• Previous experience working in a cGMP or cGLP regulated environment.
• Familiarity with Cellario, Venus (Hamilton), or OneLab (Andrew+) automation platforms.
• Experience developing and executing technology transfer plans across QC or partner functions.

Physical Requirements: Ability to work in a laboratory environment, including standing for extended periods and handling laboratory equipment.

Gowning & Environment: This role operates in a GMP analytical laboratory. Appropriate gowning and PPE are required in designated areas.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed onsite. Please speak with your recruiter and hiring manager for more information about onsite expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)

$92,200.00 - $150,600.00

Benefits (annual package includes)

• annual bonuses or other incentive plans
• equity awards
• pension or retirement benefits
• 401(k) company match
• health and wellness programs
• fitness centers
• insurance benefits (e.g. medical, dental, vision, life and disability)
• paid time off
• family support benefits