Principal Analyst, Cell & Gene Commercial Tech

Vertex Inc.

Boston (MA)

Hybrid

USD 164,000 - 247,000

Full time

14 days+

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Job summary

Vertex Pharmaceuticals is seeking a Principal Business Analyst, Cell & Gene Therapy Commercial Technology to join the Data, Technology and Engineering team. You will shape technology solutions for a regulated biopharma commercial operation, partnering with stakeholders to define needs, map processes, and enable scalable digital capabilities across platforms and data ecosystems.

The role emphasizes strong stakeholder management, hands-on delivery, and ensuring compliance with privacy,

Qualifications

  • Bachelor’s degree in Business, Information Systems, Life Sciences, Engineering, or a related field.
  • Significant experience in business analysis, product delivery, process improvement, or related roles in regulated industries.
  • Experience supporting commercial business functions and technology platforms, preferably in life sciences.
  • Proven ability to lead complex, cross-functional initiatives with multiple stakeholders.
  • Strong experience eliciting, documenting, validating, and managing requirements.
  • Ability to analyze and improve business processes and translate them into tech-enabled solutions.
  • Experience supporting automation, AI-enabled, or digital transformation initiatives.
  • Experience across the full system delivery lifecycle: planning, requirements, testing, implementation, post-go-live.

Responsibilities

  • Partner with Commercial, Cell & Gene Therapy, and Technology stakeholders to understand strategies and challenges.
  • Lead requirements gathering, business process analysis, and solution design for complex initiatives.
  • Translate needs into detailed functional requirements, user stories, and process maps.
  • Support initiatives across patient services, order management, analytics, and data integration.
  • Define and deliver AI and automation use cases aligned to priorities.
  • Analyze current and future processes to identify automation and standardization opportunities.
  • Facilitate workshops to align stakeholders on priorities and outcomes.
  • Collaborate with product managers, architects, developers, and data teams to ensure alignment.
  • Drive business readiness including testing support, training, and change management.
  • Ensure compliance, privacy, legal, and promotional requirements are met.
  • Develop and maintain documentation: BRD, flows, use cases, impact assessments, traceability.
  • Use data and feedback to evaluate effectiveness and drive improvement.
  • Contribute to BA best practices across the organization.

Skills

Requirements documentation
Process workflow analysis
User story creation
Gap analysis
Data analysis & dashboards
Stakeholder facilitation
UAT support & test design
Change management support
CRM & commercial tech familiarity
AI-enabled solutions understanding
Agile/Hybrid delivery knowledge
Office tools proficiency

Education

Bachelor's degree in Business or related field
Advanced degree in Business/IS/Life Sciences

Tools

Jira
Confluence
Visio
Microsoft Excel
PowerPoint
Word

Job description

Vertex Pharmaceuticals is seeking a Principal Business Analyst, Cell & Gene Therapy Commercial Technology to join the Data, Technology and Engineering team. You will shape technology solutions for a regulated biopharma commercial operation, partnering with stakeholders to define needs, map processes, and enable scalable digital capabilities across platforms and data ecosystems.

The role emphasizes strong stakeholder management, hands-on delivery, and ensuring compliance with privacy,

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