Postdoctoral Researcher (Molecular & Comparative Pathobiology) - #Faculty

Johns Hopkins University; Baltimore (MD); On-site; USD 63,480 - 69,180; Full time

Job summary

Johns Hopkins University is seeking a Postdoctoral Fellow to join a cutting-edge HIV research team focused on persistence and cure strategies. The role involves molecular biology, virology, and lentiviral vector methods in a collaborative academic setting.

The successful candidate will perform complex experiments, analyze data, and contribute to manuscripts and presentations for conferences, advancing understanding of viral latency and eradication.

Qualifications

• Ph.D. in Molecular Biology, Biochemistry, Immunology or related field.
• Hands-on experience with tissue culture and molecular biology techniques.
• Proven experience with production and handling of lentiviral vectors.
• Strong data analysis skills and biostatistics exposure.
• Track record of independent research and publications.

Responsibilities

• Conduct complex experiments involving tissue culture, lentiviral packaging, DNA isolation, PCR, Western blotting, flow cytometry and ELISA.
• Develop and optimize assays for HIV-1 latency reversal and eradication strategies.
• Perform cell culture with mammalian cells and transduction.
• Analyze datasets to interpret results and generate insights.
• Maintain meticulous records and contribute to publications.

Education

Ph.D. in Molecular Biology, Biochemistry, Immunology or related field

Tools

Lentiviral vector production

Job description

We are seeking a highly motivated and detail-oriented Postdoctoral Fellow to join our cutting-edge research team focused on HIV-1 persistence and cure strategies. This dynamic role offers an exciting opportunity to contribute to transformative scientific discoveries in the field of HIV research, utilizing advanced molecular biology, virology, and lentiviral vector methods. The ideal candidate will thrive in a collaborative environment, demonstrate technical proficiency in laboratory methods, and possess a passion for advancing understanding of viral latency and eradication. This paid position provides comprehensive research experience in a vibrant academic or research institution dedicated to innovative health solutions.

Duties

• Conduct complex experiments involving tissue culture, lentiviral packaging and titration, DNA isolation, PCR, Western blotting, flow cytometry, ELISA, and immunoassays to investigate HIV-1 persistence mechanisms
• Develop and optimize assays related to HIV-1 latency reversal and eradication strategies
• Perform cell culture experiments with mammalian cells, including lentiviral transduction
• Analyze datasets to interpret experimental results and generate scientific insights
• Maintain meticulous laboratory records documenting experimental procedures, results, and data analysis outcomes in compliance with research standards
• Collaborate with multidisciplinary teams on projects involving development of innovative HIV-1 cure strategies, molecular biology techniques, and biochemical assays
• Contribute to scientific publications by preparing figures, writing manuscripts, and presenting findings at conferences or seminars
• Ph.D. in Molecular Biology, Biochemistry, Immunology or related field with demonstrated research experience in cell & molecular biology techniques and production of lentiviral vectors
• Proven expertise in tissue culture methods including mammalian cell culture and transfection procedures
• Hands-on experience with DNA isolation, PCR amplification, Western blotting, flow cytometry (cytometry), and immunoassays such as ELISA
• Familiarity with assay development for HIV-1 latency studies or similar viral persistence models is highly desirable
• Strong data analysis skills using biostatistical methods
• Track record of scientific publications demonstrating independent research capabilities in relevant fields
• Excellent record-keeping skills with attention to detail; ability to work effectively within a team environment in a fast-paced research setting

Salary: $63,480 - $69,180

Salary Range

The referenced salary range represents the minimum and maximum salaries for this position and is based on Johns Hopkins University's good faith belief at the time of posting. Not all candidates will be eligible for the upper end of the salary range. The actual compensation offered to the selected candidate may vary and will ultimately depend on multiple factors, which may include the successful candidate's geographic location, skills, work experience, internal equity, market conditions, education/training and other factors, as reasonably determined by the University.

Total Rewards

Johns Hopkins offers a total rewards package that supports our employees' health, life, career and retirement. More information can be found here: https://hr.jhu.edu/benefits-worklife/.

Equal Opportunity Employer

The Johns Hopkins University is committed to equal opportunity for its faculty, staff, and students. To that end, the university does not discriminate on the basis of sex, gender, marital status, pregnancy, race, color, ethnicity, national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status or other legally protected characteristics. The university is committed to providing qualified individuals access to all academic and employment programs, benefits and activities on the basis of demonstrated ability, performance and merit without regard to personal factors or demographic characteristics that are irrelevant to the program involved.

Pre-Employment Information

If you are interested in applying for employment with Johns Hopkins University and require special assistance or accommodation during any part of the pre-employment process, please contact the HR Business Services Office at [e-mail]. For TTY users, call via Maryland Relay or dial 711. For more information about workplace accommodations at Johns Hopkins University for disabilities, medical conditions (including medical conditions related to pregnancy or childbirth), accessibility, or religious reasons, please visit accessibility.jhu.edu.

Background Checks

After receiving a conditional offer, the successful candidate(s) for this position will be subject to a pre-employment background check including education verification. When deciding whether a candidate's conviction history is job-disqualifying, the University considers the nature and gravity of the offense, the time that has passed since the conviction, and the nature of the job being sought.

EEO is the Law

https://www.eeoc.gov/employees-job-applicants

Vaccine Requirements

Johns Hopkins University strongly encourages, but no longer requires, at least one dose of the COVID-19 vaccine. This change does not apply to the School of Medicine (SOM). SOM hires must be fully vaccinated with an FDA COVID-19 vaccination and provide proof of vaccination status. We still require all faculty, staff, and students to receive the seasonal flu vaccine.

Exceptions to the seasonal flu vaccine or COVID-19 vaccine (for SOM) requirement(s) may be provided to individuals with sincerely held religious beliefs or medical conditions that preclude them from receiving the vaccine. Requests for an exception must be submitted to the JHU vaccination registry. For additional information, applicants for SOM positions should visit https://www.hopkinsmedicine.org/coronavirus/covid-19-vaccine/ and all other JHU applicants should visit https://covidinfo.jhu.edu/health-safety/covid-vaccination-information/.

The following additional vaccine requirements may apply, depending upon your campus. Please contact the hiring department for more information.

The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those candidates who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.

Job Type: Full Time