Postdoctoral Research Associate - Pulmonary & Critical Care Medicine

Washington University in St. Louis; St. Louis (MO); On-site; USD 55,000 - 75,000; Full time

Job summary

Washington University in St. Louis invites applications for a postdoctoral position in the Choudhury laboratory, Department of Medicine, Division of Pulmonary & Critical Care Medicine.

The researcher will study cellular metabolism and signaling in lung fibrosis using mouse models and human tissue slices, with a focus on translating findings to therapeutic targets. The ideal candidate has a PhD/MD with experience in biochemistry, cell biology, and flow cytometry; strong communication skills and a

Qualifications

• PhD or equivalent terminal degree required.
• Experience in biochemistry and cell/molecular biology strongly preferred.
• Background in immunology and flow cytometry is advantageous.

Responsibilities

• Designs and conducts independent experiments under supervision of the PI.
• Keeps detailed records and documents experimental results.
• Analyzes and summarizes data; prepares publications and presentations.
• Maintains animal models and conducts relevant wet-lab work.
• Contributes to grant proposals and manuscript preparation.

Skills

Mouse models

Flow cytometry

Molecular biology

Biochemistry

Immunology

Single-cell RNA-seq

Publication

Independent work

Data analysis

Cell sorting

Education

PhD or MD

Tools

Knockout mouse models

Single-cell RNA-seq

Confocal imaging

Job description

Position Summary

A postdoctoral position is available immediately at the laboratory of Dr. Choudhury in the Department of Medicine, Division of Pulmonary & Critical Care Medicine at WashU in St. Louis. The Choudhury lab investigates the cellular, molecular, and metabolic mechanisms involved in the development of fibrotic disorders, including idiopathic pulmonary fibrosis, using novel mouse models and human precision-cut lung slices to study how metabolic networks may reveal disease- and context-specific targets for selectively interrupting pathological cellular functions and how these metabolic adapations may be targeted therapeutically. Our research employs cell signaling and metabolism, fibroblast-immune cell crosstalk, metabolomics, mitochondrial biology, molecular and cellular biology, genetically modified mice, lung fibrosis models, single-cell RNA sequencing, and epigenetics. We are seeking a highly motivated postdoctoral candidate with prior experience in biochemistry and cell and molecular biology; a background in immunology and expertise in flow cytometry and cell sorting and single-cell RNA sequencing are strongly preferred. The ideal candidate will be self-motivated, collaborative, and eager to contribute to complex research studies, experiments, and assays in a supportive environment that values teamwork, dedication, and curiosity. This position also offers the opportunity to develop exciting, cutting-edge independent translational research projects at the intersection of metabolism and cell signaling.

Location

SAINT LOUIS, MO 63110

Job Description

Primary Duties & Responsibilities

Information on being a postdoc at WashU in St. Louis can be found at https://postdoc.wustl.edu/prospective-postdocs-2/.

• Works independently but in close consultation with the Principal Investigator.
• Designs and performs experiments.
• Keeps appropriate experimental records and documentation.
• Analyzes, interprets, summarizes, and compiles data.
• Operates and maintains relevant animal models.
• Participates in publications and presentations as an author or co-author.
• Develops proficiency in career development skills, including writing, public speaking, networking, and critical evaluation of scientific literature.
• Maintains conformity with ethical standards in research.
• Assists in preparation of grant proposals and may also apply for mentored training grant with PI support.
• Collegial conduct towards co-trainees, staff members and members of the research group.

Working Conditions

This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.

Salary Range

Base pay is commensurate with experience.

The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.

Education

Ph.D., M.D. Or Equivalent Terminal Or Doctoral Degree.

Certifications / Professional Licenses

No specific certification/professional license is required for this position.

Work Experience

No specific work experience is required for this position.

Skills

Not Applicable

Driver's License

A driver's license is not required for this position.

Preferred Qualifications

• A recent PhD in Biochemistry, Cell or Molecular Biology with background in immunology.
• Hands-on experience with mouse work and knockout mouse models.
• Excellent written and verbal communication skills.
• Ability to work independently on research projects designed by a mentor within area of specialization.
• Hands-on experience with flow cytometry and cell sorting, fluorescence and confocal imaging, standard biochemistry, molecular/cell biology techniques, cell culture, flow cytometry, data acquisition and data analysis, gene expression, single cell RNAseq/bioinformatics analysis.
• Strong publication record in peer-reviewed journals.

Education

No additional education unless stated elsewhere in the job posting.

Preferred Qualifications

No additional education unless stated elsewhere in the job posting.

Certifications / Professional Licenses

No additional certification/professional licenses unless stated elsewhere in the job posting.

Work Experience

No additional work experience unless stated elsewhere in the job posting.

Skills

Collaboration, Data Analysis, Data Interpretations, Experimentation, Laboratory Operations, Laboratory Techniques, Researching, Results Reporting, Scientific Writing

Questions

For frequently asked questions about the application process, please refer to our External Applicant FAQ.

Accommodation

If you are unable to use our online application system and would like an accommodation, please email [e-mail] or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.

All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.

Pre-Employment Screening

All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Benefits Statement

Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits.

EEO Statement

Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.