Postdoctoral Research Associate - Infectious Diseases

UNKNOWN; United States; On-site; USD 60,000 - 70,000; Full time

Job summary

Washington University in St. Louis seeks a Postdoctoral Research Associate in the Kotov lab to study innate immunity during Mycobacterium tuberculosis infection.

The role focuses on plasmacytoid dendritic cells, macrophages, and neutrophils using mouse models in a BSL3 facility. The ideal candidate is motivated, independent, and capable of leading projects, with experience in flow cytometry, microscopy, single-cell RNA-sequencing, and spatial transcriptomics; wet-lab work complemented by dry-lab

Qualifications

• Ph.D., M.D. or equivalent terminal/doctoral degree.
• No specific certification required.
• No specific work experience required.

Responsibilities

• Train under supervision and lead projects on host response to Mtb.
• Perform basic bioinformatics on single-cell RNA-sequencing and spatial datasets.
• Mentor undergrads and rotating graduate students.
• Present at national/international conferences and write manuscripts.

Skills

Collaboration

Scientific writing

Data analysis

Mentoring

Education

Ph.D., M.D. or equivalent terminal/doctoral degree

Tools

Flow cytometry

Microscopy

Bulk and single-cell RNA-sequencing

Spatial transcriptomics

Job description

Location SAINT LOUIS, MO 63110 Position Summary

In support of a recently funded NIH DP2 award, we are looking for a cellular immunologist to join the Kotov lab as a Postdoctoral Research Associate. We focus on the innate immune response to Mycobacterium tuberculosis (Mtb) infection as it is the leading cause of death from a single pathogen worldwide. Our goal is to understand the host response to this infection to identify novel targets for host-directed therapies. There are a number of projects available, all of which focus on the host response during Mtb infection, with a primary focus on plasmacytoid dendritic cells, macrophages, and neutrophils. The ideal candidate will be motivated, independent, and collegial, with the expectation that they will lead a project or two. This position is primarily a wet lab position (though has dry lab components!) involving the use of mouse models in an animal BSL3 facility. Previous BSL3 experience is not a requirement. Candidates with experience with mice, flow cytometry, and microscopy are encouraged to apply. Additionally, previous experience analyzing transcriptomic data is an advantage, as the dry lab (e.g., single cell RNA-sequencing dataset analysis) informs the wet lab work.

Job Description Primary Duties & Responsibilities

For more information about the Kotov lab, please visit https://kotovlab.wustl.edu/. Information on being a postdoc at WashU in St. Louis can be found at https://postdoc.wustl.edu/prospective-postdocs-2/.

• Trains under the supervision of a faculty mentor including (but not limited to): Leverage cellular immunology techniques (flow cytometry, microscopy, bulk and single cell RNA-sequencing, spatial transcriptomics) to study the host response against Mtb infection using mouse models in a BSL3 facility.
• Perform basic bioinformatics analysis of single cell RNA-sequencing and spatial transcriptomic datasets.
• Mentor undergraduates, research technicians, and rotating graduate students.
• Collaborate with researchers inside and outside of Washington University in St. Louis.
• Present at national and international conferences.
• Write manuscripts.

Working Conditions

This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.

Salary Range

Base pay is commensurate with experience. The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.

Required Qualifications

Education: Ph.D., M.D. Or Equivalent Terminal Or Doctoral Degree.

Certifications/Professional Licenses: No specific certification/professional license is required for this position.

Work Experience: No specific work experience is required for this position.

Skills: Not Applicable.

Driver's License: A driver's license is not required for this position.

More About This Job At WashU, postdoctoral appointments:

Have a 5-year term limit that includes previous experience.

Preferred Qualifications

Education: No additional education unless stated elsewhere in the job posting.

Certifications/Professional Licenses: No additional certification/professional licenses unless stated elsewhere in the job posting.

Work Experience: No additional work experience unless stated elsewhere in the job posting.

Skills: Collaboration, Data Analysis, Data Interpretations, Experimentation, Laboratory Operations, Laboratory Techniques, Researching, Results Reporting, Scientific Writing.

Accommodations

If you are unable to use our online application system and would like an accommodation, please email [e-mail] or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request. All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.

Pre-Employment Screening

All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Benefits Statement

Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits.

EEO Statement

Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.

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