Postdoctoral Fellow: Tumor Immunology & Microenvironment

Boehringer Ingelheim GmbH; Ridgefield (CT); On-site; USD 68,000 - 92,000; Full time

Job summary

Boehringer Ingelheim is seeking a Post Doctoral Fellow to develop human tumor ecosystem models and dissect immune suppression in the tumor microenvironment at our Ridgefield, CT site. You will design innovative 3D/ex vivo systems, apply CRISPR perturbations, and generate data across multi-omics readouts to advance immuno-oncology programs.

The role emphasizes independent research under a PI with opportunities to publish and collaborate across internal groups and external partners.

Qualifications

• Ph.D. in tumor immunology, cancer biology, immunology, or related discipline (preferred 0–3 years postdoc).
• Strong publication record demonstrating scientific independence and innovation.
• Deep knowledge of suppressive tumor microenvironment biology and anti-tumor immunity.
• Hands-on experience with tumor-immune cell co-cultures and 3D/ex vivo models.
• Experience with genetic perturbation techniques including CRISPR.
• Ability to design, optimize, and execute complex research projects and workflows.
• Experience with quantitative data analysis and interpretation of multidimensional datasets.
• Experience with multi-omics, high-content imaging, or spatial biology workflows is preferred.
• Exceptional scientific writing, presentation, and collaboration skills.

Responsibilities

• Design and conduct independent research on immune suppression in human tumors.
• Develop advanced multicellular co-culture systems with primary immune cells and tumor-derived cells.
• Establish ex vivo tumor models from patient-derived materials.
• Apply CRISPR-based perturbations to study suppressive pathways.
• Integrate multi-omics, high-content imaging, and spatial readouts to map immune suppression.
• Publish first-author manuscripts and contribute to patents as applicable.
• Collaborate with Boehringer Ingelheim researchers and external partners.
• Present work to leadership and at national/international conferences.

Skills

CRISPR perturbations

Multicellular co-cultures

3D/ex vivo models

Multi-omics

High-content imaging

Spatial biology

Data analysis

Scientific writing

Presentation skills

Collaboration

Education

Ph.D. in tumor immunology/cancer biology/immunology or related discipline

Tools

CRISPR-based approaches

Job description

Boehringer Ingelheim is seeking a Post Doctoral Fellow to develop human tumor ecosystem models and dissect immune suppression in the tumor microenvironment at our Ridgefield, CT site. You will design innovative 3D/ex vivo systems, apply CRISPR perturbations, and generate data across multi-omics readouts to advance immuno-oncology programs.

The role emphasizes independent research under a PI with opportunities to publish and collaborate across internal groups and external partners.