Postdoc: Single-Cell & Spatial Immunology

Merck & Co.

Cambridge (MA)

On-site

USD 87,000 - 137,000

Full time

2 days ago
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Benefits offered by this job

Annual bonus
Long-term incentive
Comprehensive benefits

Job summary

Merck & Co. is seeking a Postdoctoral Research Fellow to advance single-cell and spatial transcriptomics in immune-mediated inflammatory diseases.

You will analyze large-scale datasets from human tissues, identify disease-driving programs, and develop translational biomarkers that bridge biology and therapy. The role sits at the intersection of computational biology, immunology, and translational medicine, with exposure to cutting-edge multi-omics and tissue atlases across HS and related

Qualifications

  • PhD in a relevant field by spring 2027.
  • Strong programming skills in R and/or Python.
  • Experience analyzing large-scale genomics or multi-omics datasets.
  • Hands-on experience with GPU computing, HPC, and AWS for large-scale analyses.
  • Publication record in computational biology, genomics, immunology, or related fields.
  • Strong scientific communication, presentation, and collaboration skills.

Responsibilities

  • Analyze large-scale scRNA-seq and spatial transcriptomics data.
  • Develop and implement data integration, annotation methods.
  • Apply ML and network biology to interpret results.
  • Integrate multi-omics and clinical data to generate insights.
  • Collaborate with immunologists, translational scientists, and computational researchers.
  • Lead publication-quality analyses and manuscripts.
  • Present findings at internal forums and external conferences.
  • Develop reusable computational resources and methods.
  • Collaborate across DAGS, Immunology Discovery, and Translational Medicine teams.

Skills

R/Python programming
Genomics/multi-omics analysis
GPU/HPC/AWS cloud
Pipeline development for scRNA-seq/spa
Publication record in relevant field
Scientific communication & teamwork

Education

PhD in Computational Biology/Bioinformatics/Systems Biology/Genomics/CS/Statistics or related

Tools

Seurat/Scanpy/scVI
GPU computing frameworks
AWS Cloud

Job description

Merck & Co. is seeking a Postdoctoral Research Fellow to advance single-cell and spatial transcriptomics in immune-mediated inflammatory diseases.

You will analyze large-scale datasets from human tissues, identify disease-driving programs, and develop translational biomarkers that bridge biology and therapy. The role sits at the intersection of computational biology, immunology, and translational medicine, with exposure to cutting-edge multi-omics and tissue atlases across HS and related

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