Postdoctoral Fellow - Translational Molecular Pathology

UT MD Anderson; Houston (TX); On-site; USD 64,000 - 76,000; Full time

Benefits offered by this job

Medical benefits

Dental benefits

Paid time off

Retirement benefits

Tuition benefits

Educational opportunities

Individual and team recognition

Job summary

UT MD Anderson in Houston is seeking a dedicated Postdoctoral Fellow in Translational Molecular Pathology to conduct comprehensive laboratory research on DNA damage response networks and repair pathways. This full-time position will focus on understanding the interplay between tumor biology and therapeutic sensitivity, aiming to develop precise diagnostic strategies.

Ideal candidates will hold a recent Ph.D. and are expected to work under a faculty mentor to advance their academic and research careers. The role offers competitive salary and excellent benefits.

Qualifications

• Recent Ph.D. or equivalent doctorate within the last three years.
• Experience with biochemical and cell biological systems.
• Understanding of DNA damage and repair mechanisms.

Responsibilities

• Conduct full-time laboratory-based research on DNA damage response.
• Investigate cellular damage sensing and repairactivation.
• Characterize processes altered in specific disease states.

Education

Ph.D. or equivalent doctorate in an appropriate field

Job description

The department of Translational Molecular Pathology seeks a Postdoctoral Fellow to join a new laboratory focusing on elucidating the molecular architecture of DNA damage response networks, DNA repair pathways, and their functional interplay with tumor biology and therapeutic sensitivity. The research integrates methodologies from biochemistry, high-throughput genomics and translational research to systematically characterize how malignant cells detect, signal and resolve genotoxic stress. These efforts advance mechanistic insight into cancer cell vulnerabilities and inform the development of more precise diagnostic strategies and targeted therapeutic interventions.

All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations.

LEARNING OBJECTIVES

• Learn how to use a variety of biochemical, cell biological, and animal model systems to better understand the human genome and repair mechanisms used for repairs needed to maintain cell viability and prevent oncogenesis caused by endogenous and exogenous forms of damage.
• Investigate how human cells sense such damage and activate repair, and how/if processes are altered in specific disease states.
• Understand how the cell promotes DNA repair in the context of chromatin, transcription, and different stages of the cell cycle, and the role RNA damage may have in cells.

Eligibility Requirements

An individual holding a recent (within three years) Ph.D. or equivalent doctorate (e.g., Sc.D., M.D., D.V.M.) in an appropriate field who is seeking a temporary appointment, under the supervision of a faculty mentor, involving full-time laboratory-based research or scholarship in preparation for an academic or research career as an independent investigator. This appointment is not part of a clinical training program; individuals holding an M.D. degree or equivalent are not permitted to engage in patient care activity.

POSITION INFORMATION

MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000 depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition.

Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements.

This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment.

It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html