Postdoctoral Fellow – Single-Cell Genomics & CRISPR Technology Development

Genentech; South San Francisco (CA); On-site; USD 100,000 - 107,000; Full time

Benefits offered by this job

Relocation benefits

Job summary

Genentech in South San Francisco seeks a Postdoctoral Fellow to drive technology development at the forefront of functional genomics, focusing on single-cell multi-omics and CRISPR-based perturbation screens. You will work with Darmanis and Regev labs, solving fundamental biological questions and delivering publishable science.

The program offers mentorship, seminars, and fully funded research expenses, with competitive salaries and relocation benefits to support your career as a scientific

Qualifications

• Education: PhD (or near completion) in Molecular Biology, Genetics, Biochemistry, Biomedical Engineering, Bioengineering, or related field.
• Core Technical Expertise: Strong background in molecular biology, genomics, cell biology, or bioengineering, with ability/enthusiasm to apply single-cell multi-omic assays or CRISPR-based tech.
• Sequencing Experience: Proficient in standard molecular biology techniques and NGS library preparation downstream of single-cell assays; exposure to short- and long-read sequencing.
• Data Analysis: Working knowledge of computational genomics analysis using R and/or Python.
• Publication Record: Demonstrated track record of productivity (first-author pubs, preprints, or patents).
• Soft Skills: Excellent oral and written communication, problem-solving, collaborative mindset.

Responsibilities

• Spearhead design, development, and optimization of single-cell multi-omic tech, focusing on high-throughput CRISPR perturbation screens.
• Interpret and analyze complex single-cell genomics data using diverse analytical methods and AI-based approaches.
• Collaborate with academic and scientific partners to advance novel platforms.
• Publish primary research in high-impact journals and present findings at seminars and conferences.

Skills

Molecular biology

Genomics

Cell biology

Bioengineering

CRISPR technology

Single-cell multi-omics

R

Python

Scientific writing

Collaboration

Education

PhD

Tools

NGS platforms

Job description

The Position

Why Genentech

We advance science so that we all have more time with the people we love.

Innovating for a healthier future is our driving force. The Darmanis and Regev labs are seeking a creative, rigorous, and motivated Postdoctoral Fellow to focus on technology development at the forefront of functional genomics, developing single-cell, CRISPR-based genetic perturbation screens and multi-omic technologies. You will engage with scientific collaborators across the community to solve fundamental biological questions and publish high-impact science.

The Opportunity

• Spearhead the design, development, and optimization of novel technologies for single-cell multi-omics, with a primary focus on high-throughput CRISPR genetic perturbation screens.
• Interpret and analyze complex single-cell genomics data using a variety of analytical methods and AI-based approaches.
• Collaborate with academic and scientific partners to advance novel technological platforms.
• Publish primary research in high-impact, peer-reviewed scientific journals and present scientific findings at internal seminars and international conferences.

Who You Are

• Education: PhD (or near completion) in Molecular Biology, Genetics, Biochemistry, Biomedical Engineering, Bioengineering, or a related scientific discipline.
• Core Technical Expertise: Strong background in molecular biology, genomics, cell biology, or bioengineering, with a demonstrated ability or enthusiasm to learn and apply single-cell multi-omic assays or CRISPR-based technologies.
• Sequencing Experience: Proficient in standard molecular biology techniques and NGS library preparation downstream of single-cell assays, with exposure to short- and long-read sequencing platforms.
• Data Analysis: Working knowledge of or proficiency in computational genomics analysis using R and/or Python.
• Publication Record: Demonstrated track record of scientific productivity, evidenced by first-author publications, preprints, or patent applications.
• Soft Skills: Excellent oral and written communication skills, strong problem-solving abilities, and an eagerness to thrive in a collaborative research environment.

The Postdoc Program

Elevate your research career to new heights with Genentech's Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions.

The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader.

The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities.

The expected salary range for this position based on the primary location of California is $100,000 to $106,500 .Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Relocation benefits are available for this job posting.

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants .