Postdoctoral Fellow — Scorletti Lab

Johns Hopkins University; Baltimore (MD); On-site; USD 63,000 - 77,000; Full time

Job summary

The Johns Hopkins University School of Medicine, Baltimore, Maryland, invites applications for a Postdoctoral Fellow in the Scorletti Lab to study how genetic variants influence lipid metabolism in liver and adipose tissue using iPSC-derived hepatocytes, organoids, and related models.

The successful candidate will design experiments, analyze data, contribute to manuscripts, and develop new research directions within a collaborative team.

Qualifications

• Hands-on experience with mammalian cell culture and molecular biology techniques such as Western blotting, PCR/qPCR, immunostaining and microscopy.
• Experience with iPSCs, especially iPSC‑derived hepatocytes, and/or organoid models is highly desirable.
• Experience with computational data analysis (R or Python) and use of AI tools to support coding and data analysis.

Responsibilities

• Lead projects using iPSC-derived hepatocytes, organoids, and other in vitro models to investigate cellular mechanisms.
• Contribute to experimental design, data analysis and interpretation, and manuscript preparation.
• Develop new research directions and collaborate across the Scorletti Lab and center.

Skills

Cell culture

Molecular biology

Mammalian cells

Western blot

PCR/qPCR

Immunostaining

Microscopy

iPSCs

Organoid models

R

Python

AI tools

Education

PhD in cell biology

Tools

R

Python

Job description

PosPostdoctoral Fellow — Scorletti Lab

Johns Hopkins, founded in 1876, is America's first research university and home to nine world-class academic divisions working together as one university.

Salary : $63,480-$77,076 depending on year of PhD received

Johns Hopkins University: School of Medicine: Department of Medicine: Gastroenterology

Description

Division of Gastroenterology and Hepatology, Department of Medicine Johns Hopkins University School of Medicine, Baltimore, Maryland

The laboratory of Dr. Eleonora Scorletti at the Johns Hopkins University School of Medicine is recruiting a highly motivated Postdoctoral Fellow. The Scorletti Lab combines recall-by-genotype studies, deep clinical phenotyping, and human cellular models to investigate how naturally occurring genetic variants influence lipid metabolism in the liver and adipose tissue, with implications for metabolic health and aging.

The successful candidate will lead projects that build on our K99/R00-supported research, using induced pluripotent stem cell (iPSC)-derived hepatocytes, organoids, and other in vitro models to investigate the cellular mechanisms underlying findings from human studies. The fellow will contribute to experimental design, data analysis and interpretation, manuscript preparation, and the development of new research directions.

Qualifications

Candidates should have hands‑on experience with mammalian cell culture and molecular and cellular biology techniques, such as Western blotting, PCR/qPCR, immunostaining, and microscopy. Experience with iPSCs, particularly iPSC‑derived hepatocytes, and/or organoid models is highly desirable. Experience with computational data analysis (e.g., R or Python) and the effective use of AI tools (e.g., ChatGPT, Claude) to support coding and data analysis is a plus.

We seek applicants with a strong interest in lipid metabolism, scientific curiosity, and enthusiasm for learning new techniques and establishing new experimental models. Strong organizational and communication skills, along with the ability to work independently and collaboratively, are essential.

Applicants should hold a PhD in cell biology, molecular biology, biochemistry, genetics, physiology, or a related discipline, or expect to have the degree conferred by the position start date. Candidates should also have at least one first‑author, peer‑reviewed publication demonstrating their ability to conduct and communicate original research.

Mentorship and Career Development

The Scorletti Lab is strongly committed to the career development and scientific independence of its trainees. The fellow will receive dedicated mentorship in experimental design, scientific writing, and grantsmanship, including active support for individual fellowship and career development award applications (e.g., F32, K99) and funded travel to national and international conferences. Postdoctoral fellows at Johns Hopkins also benefit from the School of Medicine's Professional Development and Career Office and an active postdoctoral association, which offer extensive training, networking, and career development programming.

Salary Range

The referenced salary range represents the minimum and maximum salaries for this position and is based on Johns Hopkins University's good faith belief at the time of posting. Not all candidates will be eligible for the upper end of the salary range. The actual compensation offered to the selected candidate may vary and will ultimately depend on multiple factors, which may include the successful candidate's geographic location, skills, work experience, internal equity, market conditions, education/training and other factors, as reasonably determined by the University.

Total Rewards

Johns Hopkins offers a total rewards package that supports our employees' health, life, career and retirement. More information can be found here: https://hr.jhu.edu/benefits-worklife/.

Equal Opportunity Employer

The Johns Hopkins University is committed to equal opportunity for its faculty, staff, and students. To that end, the university does not discriminate on the basis of sex, gender, marital status, pregnancy, race, color, ethnicity, national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status or other legally protected characteristics. The University is committed to providing qualified individuals access to all academic and employment programs, benefits and activities on the basis of demonstrated ability, performance and merit without regard to personal factors or demographic characteristics that are irrelevant to the program involved.

Pre-Employment Information

If you are interested in applying for employment with Johns Hopkins University and require special assistance or accommodation during any part of the pre‑employment process, please contact the HR Business Services Office at [e-mail]. For TTY users, call via Maryland Relay or dial 711. For more information about workplace accommodations at Johns Hopkins University for disabilities, medical conditions (including medical conditions related to pregnancy or childbirth), accessibility, or religious reasons, please visit accessibility.jhu.edu.

Background Checks

After receiving a conditional offer, the successful candidate(s) for this position will be subject to a pre‑employment background check including education verification. When deciding whether a candidate’s conviction history is job‑disqualifying, the University considers the nature and gravity of the offense, the time that has passed since the conviction, and the nature of the job being sought.

EEO is the Law

https://www.eeoc.gov/employees-job-applicants

Vaccine Requirements

Johns Hopkins University strongly encourages, but no longer requires, at least one dose of the COVID-19 vaccine. This change does not apply to the School of Medicine (SOM). SOM hires must be fully vaccinated with an FDA COVID-19 vaccination and provide proof of vaccination status. We still require all faculty, staff, and students to receive the seasonal flu vaccine.

Exceptions to the seasonal flu vaccine or COVID-19 vaccine (for SOM) requirement(s) may be provided to individuals with sincerely held religious beliefs or medical conditions that preclude them from receiving the vaccine. Requests for an exception must be submitted to the JHU vaccination registry. For additional information, applicants for SOM positions should visit https://www.hopkinsmedicine.org/coronavirus/covid-19-vaccine/ and all other JHU applicants should visit https://covidinfo.jhu.edu/health-safety/covid-vaccination-information/.

The following additional vaccine requirements may apply, depending on your campus. Please contact the hiring department for more information.

The pre‑employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre‑employment physical exam except for those candidates who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.