Postdoctoral Fellow (Myers Lab)

La Jolla Institute for Immunology; San Diego (CA); On-site; USD 70,000 - 120,000; Full time

Job summary

La Jolla Institute for Immunology in San Diego invites a highly motivated postdoctoral researcher to develop and apply state-of-the-art proteomics technologies to address fundamental questions in early development and immune function. The Myers Lab focuses on protein mass spectrometry and proteomics to understand signaling circuits that control transcriptional responses.

Successful candidates will join a highly collaborative environment at a world-leading nonprofit housing 20 world-renowned

Qualifications

• MD/PhD or equivalent in analytical chemistry, chemical biology, biochemistry, or related field.
• Expertise in high-end mass spectrometry-based proteomics, including sample prep, data acquisition, quantitation, and interpretation.
• Strong publication record in peer-reviewed journals.
• Excellent verbal and written communication for collaboration.
• Proven track record of independent, creative research.

Responsibilities

• Develop and apply state-of-the-art proteomics technologies to address questions in early development and immune function.
• Collaborate across disciplines within a world-leading nonprofit research environment.
• Contribute to experimental design, data analysis, and interpretation for high-impact projects.

Skills

Mass spectrometry-based proteomics

Analytical chemistry

Scientific writing & communication

Independent researcher

Education

MD, Ph.D., or equivalent in related field

Job description

The Myers Lab and the Laboratory for Immunochemical Circuits at the La Jolla Institute for Immunology (https://www.samyerslab.org/) is looking for a highly motivated postdoctoral researcher to develop and apply state-of-the-art proteomics technologies to address fundamental yet elusive questions in early development and immune function. The Myers Lab develops and applies interdisciplinary approaches, centered around protein mass spectrometry and proteomics, to understand the dynamic biochemical circuits cells use to interpret their environment and drive transcriptional responses.

Some examples of research areas in the lab that need creative, interdisciplinary approaches include:

• The development and optimization of enrichment strategies for the global, quantitative analysis of posttranslational modifications
• Understanding the crosstalk and integration of multiple signaling pathways and signaling chemistries that drive stem and immune cell differentiation
• Structural and functional characterization of protein complexes involved in glycosylation signaling and their role in transcriptional/epigenetic regulation

Successful candidates will join a highly collaborative and interdisciplinary environment. The La Jolla Institute is a world-leading non-profit research organization that hosts 20 world-renowned faculty and over 200 postdoctoral researchers hailing from 30+ different countries. LJI is located in the Science Research Park on the campus of UC San Diego, with easy access to the San Diego life sciences community and all that the area has to offer.

Qualified Candidates should have:

• An MD, Ph.D., or equivalent experience in analytical chemistry, chemical biology, biochemistry, or a related field
• Expertise in high-end mass spectrometry-based proteomics, including sample preparation, data acquisition, quantitation, and data analysis and interpretation
• Strong scientific productivity, demonstrated through high-quality research published in peer-reviewed journals
• Excellent verbal and written communication skills for internal and collaborative projects
• A track record of creative and independent research
• A strong sense of curiosity and willingness to explore

Strong applicants will have knowledge or skills in one or more of the following areas:

• Statistical analysis, Mathematical modeling, and/or Computational Biology
• Immunology and/or immune signaling pathways
• Biochemistry and Molecular Biology
• Structural Biology (protein complex characterization, cross-linking mass spectrometry, etc.)
• Genome editing and genomic engineering