Postdoctoral Fellow-MSH

Mount Sinai Health System; New York (NY); On-site; USD 72,000 - 80,000; Full time

Job summary

Join the Mount Sinai Health System as a Postdoctoral Fellow-MSH, where you will contribute to groundbreaking research in liver cancer. This role offers a unique opportunity to work in a dynamic lab focused on genetic alterations and their impact on treatment responses. Candidates should hold a Ph.D. in molecular or cell biology, with added computational and mouse experience considered advantageous. Become part of a renowned institution dedicated to innovation and excellence in patient care.

Qualifications

• Ph.D. in a relevant field expected.
• Computational skills highly beneficial.
• Experience with mouse models is a plus.

Responsibilities

• Study mechanisms of liver cancer initiation and maintenance.
• Utilize mouse models and patient samples in research.
• Collaborate effectively within the research team.

Skills

Research skills

Strong communication skills

Computational skills

Mouse handling experience

Education

Ph.D. in molecular biology or cell biology

Job description

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Roles & Responsibilities:

Description

Roles & Responsibilities:

Dr. Amaia Lujambio´s research group studies mechanisms of liver cancer initiation and liver cancer maintenance. In particular, we are interested in how genetic alterations in cancer cells contribute to tumorigenesis, alter treatment response, and create vulnerabilities that may be targeted therapeutically. Our research interests involve the establishment of precision in vitro and in vivo systems for the study of liver cancer, as well as the rational use of shRNA and CRISPR libraries to identify drug targets for the disease. We utilize sophisticated mouse models of cancer, RNAi technology, valuable human cancer samples, and genetic and immune profiling as key tools. The ultimate goal is to improve our understanding of liver cancer and to identify novel strategies that can be exploited therapeutically to improve healthspan and longevity.

The project aims at understanding the contribution of different genetic alterations to intra-tumor heterogeneity in hepatocellular carcinoma (HCC). The project will involve the use of mouse models of liver cancer, patient tumor samples, and single-cell phenotyping by scRNA-seq, Cytof, and multiplex immunostainings.

We are accepting applications from talented and enthusiastic candidates who are interested in a dynamic, well-supported lab at a top research institution. The successful candidate must have, or be expecting, a Ph.D. in molecular biology, cell biology, or a related topic. Computational skills and mouse experience are a plus. The candidate will be expected to work well in a collaborative environment and to have strong communication skills.

Interested applicants should submit an electronic copy of their CV, the names and contact information of three referents, and a cover letter describing past research experience, research interests, and career goals

Requirements

PhD

Responsibilities

Qualifications

Employer Description

Strength through Unity and Inclusion

The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai’s unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual.

At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history.

About The Mount Sinai Health System

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report’s “Best Children’s Hospitals” ranks Mount Sinai Kravis Children's Hospital among the country’s best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.

Equal Opportunity Employer

The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization.

Compensation

The Mount Sinai Health System (MSHS) provides salary ranges that comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $72500 - $80000 Annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.

Seniority level

• Seniority level

  Not Applicable

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research

• Industries

  Hospitals and Health Care

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