Postdoctoral Fellow - GI Med Oncology - Research

University of Texas MD Anderson Cancer Center; Houston (TX); On-site; USD 64,000 - 76,000; Full time

Job summary

The University of Texas MD Anderson Cancer Center in Houston seeks a postdoctoral fellow in the GI Medical Oncology department. You will assist the PI with clinical, translational, and basic science projects, designing independent experiments focused on colorectal cancer models and multi-omics analyses.

Responsibilities include proposing innovative approaches, presenting findings, and preparing publications and grant applications, while complying with all policies and regulations.

Qualifications

• Graduate degree in medicine, science, engineering or bioinformatics is required.
• Experience with algebraic and statistical data interpretation is a plus.
• Proven ability to design, execute, and report experiments and results.

Responsibilities

• Assist PI with clinical, translational and basic science projects.
• Design and initiate independent research experiments.
• Work with in vitro and in vivo models of colorectal cancer.
• Prepare samples for RNAseq, DNAseq, spatial transcriptomics and single cell analyses.
• Perform multiplex imaging experiments and analysis.
• Write results for publications and assist with grant applications.
• Collaborate with experimental and computational lab members.

Skills

Colorectal cancer research

In vitro models

In vivo models

PDX modeling

Multiplex imaging

Genomic sequencing

RNAseq

DNAseq

Single-cell analysis

Grant writing

Scientific publishing

Independent research

Data interpretation

Education

Graduate degree in medicine, science, engineering or bioinformatics

Tools

Spatial transcriptomics

Sequencing platforms

Bioinformatics analyses

Job description

A postdoctoral fellow position is available in the department of GI Medical Oncology. The postdoctoral fellow will assist the principal investigator with clinical, translational, and basic scientific research projects. Function in a separate and independent manner in the design and initiation of research experiments. Focus on in vitro and in vivo models of colorectal cancer to understand mechanisms of drug resistance. Design animal experiments and bench related interrogation and develops approaches and submits samples for RNAseq, DNAseq, spatial transcriptomics and single cell analysis as well as other multi-omics experiments or research to obtain high-reliability results and reports. Focus on PDX and immune competent animal modeling. Performs multiplex imaging experiments and analysis to evaluate tumor heterogeneity.

Determine specific goals or objectives to be obtained, evaluates research data and develops and revises techniques or approaches to work problems.

Interface with the databases of tissue samples and tumor molecular data. Compiles, writes, and submits project results for publications. Writes grant applications independently and assists principal investigator with grant applications. Collaborates with experimental and computational members of the lab.

Additionally,

• a. Independently proposes innovative solutions to research projects and contributes to project goals research projects
• b. Interpret, present and report research findings at internal meetings and potentially external scientific conferences.

All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations.

LEARNING OBJECTIVES

• - Understanding of biology of colon, rectal, anal pancreatic cancers
• - Ability to search and evaluate clinical and scientific literature
• - Ability to form and then defend hypotheses based on prior clinical or experimental data
• - Ability to effectively communicate findings in written and oral form
• - Ability to write persuasive grant applications
• - Ability to navigate scientific publication process

ELIGIBILITY REQUIREMENTS

Graduate degree in medicine, science, engineering field or bioinformatics

POSITION INFORMATION

MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000 depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition.

Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements.

This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment.

It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law.