Postdoctoral Fellow-Genome Engineering

The Jiang Lab, The Icahn School of Medicine at Mount Sinai; New York (NY); On-site; USD 70,000 - 85,000; Full time

Benefits offered by this job

Competitive salary

Subsidized housing

Vibrant translational research env.

Job summary

The Jiang Lab at the Icahn School of Medicine at Mount Sinai, New York, seeks a highly motivated postdoctoral fellow with expertise in mammalian cell culture, transfection, electroporation, and genome editing experiments. The role includes cell-based assays, mouse models, and potentially in vivo delivery strategies to advance CRISPR tools for gene therapy.

Ideal candidates will have a PhD and experience with primary cells, differentiation, and Python-based analysis pipelines, plus strong

Qualifications

• PhD degree.
• Experience in mammalian cell culture, transfection, electroporation, cell-based assays including FACS and cell imaging, or/and stem cell culture and differentiation.
• Proficient experience with molecular biology-related experiments, such as cloning, and mouse experiments.
• Proofs of the ability to independently lead a project.
• Good written and oral communication skills.

Skills

Mammalian cell culture

Transfection

Electroporation

Cell imaging

Flow cytometry

Stem cell culture

Differentiation

Python analysis

Mouse models

Education

PhD degree

Job description

The Jiang Lab (https://labs.icahn.mssm.edu/jianglab/) at the Icahn School of Medicine at Mount Sinai, New York is seeking a highly motivated postdoctoral fellow with expertise in mammalian cell culture, transfection, and electroporation, genome editing experiments, cell-based assays (e.g., cell imaging and flow cytometry), and mouse models (e.g., in vivo delivery strategy). Experience in primary cell culture and differentiation, or/and python-based analysis pipelines is highly preferred. The goal of our lab is to develop mutation-tailored CRISPR-based genome editing tools and translate them into next-generation gene therapies to treat those untreatable human genetic diseases, such as cystic fibrosis. To achieve this, we will engineer advanced CRISPR tools to correct or model the defective genomic DNA, and further deliver these newly-engineered editors into targeted organs, e.g., lung and liver, to correct the corresponding phenotypes. The position offers a competitive salary, subsidized housing, and exposure to a highly translational and vibrant research environment at Mount Sinai and the New York City area.

The qualified candidate should have:

• PhD degree
• Proficient experience in mamaliam cell culture, transfection, electroporation, cell-based assays including FACS and cell imaging,or/and stem cell culture and differentiation.
• Proficient Experience with molecular biology-related experiments, such as cloning, and mouse experiments.
• Proofs of the ability to independently lead a project.
• Good written and oral communication skills.