Postdoctoral Fellow

University of Pennsylvania Perelman School of Medicine; Pennsylvania; On-site; USD 55,000 - 65,000; Full time

Job summary

The Wherry lab at the University of Pennsylvania, Perelman School of Medicine, invites applications for a postdoctoral fellow to join a CRI-funded immunotherapy atlas project. The position focuses on integrating data across labs and generating data-driven hypotheses using large-scale immune datasets.

Candidates will employ flow cytometry, single-cell RNA sequencing with TCR analyses, proteomics, and spatial methods to study tumor-immune interactions and translational questions bridging

Qualifications

• PhD, MD, or MD/PhD in immunology, cancer biology, or a related field.
• Strong record of productivity and ability to work independently and in a team.

Responsibilities

• Lead project in the Wherry lab and integrate data across CRI-Immunotherapy Atlas labs.
• Perform flow cytometry, scRNA (+TCR)-seq, proteomics, and spatial analyses to study the tumor-immune microenvironment.
• Generate data-driven hypotheses based on analyses of the resource.

Skills

Immunology

Cancer biology

Data analysis

Collaboration

Education

PhD/MD/MD-PhD

Tools

Flow cytometry

Single-cell RNA sequencing

Proteomics

Spatial analysis

Job description

University of Pennsylvania: Postdoctoral Positions: Perelman School of Medicine Postdoctoral

Location

University of Pennsylvania, Perelman School of Medicine

Open Date

Aug 07, 2026

Description

The Wherry lab, in the Department of Systems Pharmacology and Translational Therapeutics, has an opening for a postdoctoral fellow to join a CRI-funded research project. This position is part of a larger CRI Initiative to establish a data resource that will enable data-driven innovation in immunotherapy and address the translational gap between preclinical models and clinical trials. This Immunotherapy Altas will incorporate comprehensive immune landscapes across commonly used mouse models as well as how these landscapes are altered when immunotherapy perturbations are applied. The goal for this position is to contribute to the establishment of this resource and to use it to address data-driven hypotheses that are generated based on analyses of this resource.

The postdoctoral fellow will lead this project in the Wherry lab and be instrumental in integrating similar data across two additional CRI-Immunotherapy Atlas labs. Experimental approaches to address the tumor-immune microenvironment will include flow cytometry, scRNA (+TCR)-seq, proteomics, and spatial analysis.

This position is an excellent opportunity to learn how to master cutting-edge technologies, leverage large datasets, generate data-driven hypotheses, and become a strong collaborative scientific leader.

Qualifications

Successful candidates will have a PhD, MD, or MD/PhD degree, experience in immunology and/or cancer biology, a strong record of productivity, and a demonstrated ability to work independently and as a team.

Any questions can be directed to Dr. E. John Wherry ([e-mail])