Postdoctoral Fellow

University of Pennsylvania Perelman School of Medicine; Erie (Erie County); On-site; USD 52,000 - 68,000; Full time

Job summary

The Wherry lab at the University of Pennsylvania, Perelman School of Medicine, invites applications for a postdoctoral fellow to contribute to a CRI-funded Immunotherapy Atlas project that maps immune landscapes across mouse models and immunotherapy perturbations to advance translational insights.

The successful candidate will lead analyses of multi-omics datasets, including flow cytometry, scRNA(+TCR)-seq, proteomics, and spatial profiling, and collaborate across two additional

Qualifications

• PhD, MD, or MD/PhD in immunology or cancer biology.
• Strong record of productivity in relevant research.
• Ability to work independently and as part of a team.

Responsibilities

• Lead project in the Wherry lab and integrate data across two additional CRI-Immunotherapy Atlas labs.
• Address data-driven hypotheses generated from analyses of the resource.

Skills

Immunology

Cancer biology

Data analysis

Independence

Team collaboration

Education

PhD

MD

MD/PhD

Tools

Flow cytometry

scRNA-seq

TCR-seq

Proteomics

Spatial analysis

Job description

University of Pennsylvania: Postdoctoral Positions: Perelman School of Medicine Postdoctoral

Location

University of Pennsylvania, Perelman School of Medicine

Open Date

Aug 07, 2026

Description

The Wherry lab, in the Department of Systems Pharmacology and Translational Therapeutics, has an opening for a postdoctoral fellow to join a CRI-funded research project. This position is part of a larger CRI Initiative to establish a data resource that will enable data-driven innovation in immunotherapy and address the translational gap between preclinical models and clinical trials. This Immunotherapy Altas will incorporate comprehensive immune landscapes across commonly used mouse models as well as how these landscapes are altered when immunotherapy perturbations are applied. The goal for this position is to contribute to the establishment of this resource and to use it to address data-driven hypotheses that are generated based on analyses of this resource. The postdoctoral fellow will lead this project in the Wherry lab and be instrumental in integrating similar data across two additional CRI-Immunotherapy Atlas labs. Experimental approaches to address the tumor-immune microenvironment will include flow cytometry, scRNA (+TCR)-seq, proteomics, and spatial analysis. This position is an excellent opportunity to learn how to master cutting-edge technologies, leverage large datasets, generate data-driven hypotheses, and become a strong collaborative scientific leader.

Qualifications

Successful candidates will have a PhD, MD, or MD/PhD degree, experience in immunology and/or cancer biology, a strong record of productivity, and a demonstrated ability to work independently and as a team.