Postdoctoral Associate

Baylor College of Medicine; Houston (TX); On-site; USD 52,000 - 70,000; Full time

Job summary

Baylor College of Medicine invites applications for a Postdoctoral Associate to investigate molecular mechanisms of endogenous DNA damage in human cells and proteins that oppose these processes, with emphasis on translesion synthesis and DNA damage tolerance. The ideal candidate will have a PhD in a related field and hands-on experience in molecular biology.

This role involves wet-lab work, data analysis, manuscript preparation, and presenting findings at group meetings and conferences.

Qualifications

• MD or PhD required in Basic Science/Health Science or a related field.
• No experience required.
• Background in human DNA damage tolerance is desirable.

Responsibilities

• Performs wet-bench work, molecular biology of nucleic acids, and human-cell culture.
• Designs and works on construction of DNA expression constructs, molecular cloning.
• Works on transfections and creation of stable transductions, assays of mutation rates, and flow cytometry.
• Analyses data from multiple kinds of assays.
• Works on DNA sequencing and genomics, and other experimental methods as needed.
• Reads and reports on relevant literature.
• Presents results to the group, to collaborators and at conferences to broad audiences.
• Works on manuscript preparation and reviews papers through to publication.
• Writes applications for postdoctoral fellowships.
• Performs other job-related duties as assigned.

Skills

Molecular biology

DNA sequencing

Genomics

Flow cytometry

Education

MD or PhD in Basic Science/Health Science or related field

Tools

DNA cloning

Transfection

Job description

Work Schedule: Monday – Friday, 8:30 a.m. – 5:30 p.m.

Summary

The Postdoctoral Associate position will focus on molecular mechanisms by which endogenous, spontaneous DNA damage origniates in human cells, and human proteins that oppose those mechanisms and reduce somatic cell mutation rates. A background in human DNA damage tolerance, inclusing translesion systhesis mechanisms, is desired.

Baylor College of Medicine typically follows similar to the NIH stipulated stipend guidelines for Postdoctoral Associates.

Job Duties

• Performs wet-bench work, molecular biology of nucleic acids, and human-cell culture.
• Designs and works on construction of DNA expression constructs, molecular cloning.
• Works on transfections and creation of stable transductions, assays of mutation rates, and flow cytometry.
• Analyses data from multiple kinds of assays.
• Works on DNA sequencing and genomics, and other experimental methods as needed.
• Reads and reports on relevant literature.
• Presents results to the group, to collaborators and at conferences to broad audiences.
• Works on manuscript preparation and reviews papers through to publication.
• Writes applications for postdoctoral fellowships.
• Performs other job-related duties as assigned.

Minimum Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.

Preferred Qualifications

• PhD in transfection DNA synthesis biochemistry.
• Experience in DNA replication, DNA polymerases, and DNA damage responses.
• Experience in human DNA damage tolerance, including trans lesion synthesis mechanisms, is desired.

Baylor College of Medicine fosters diversity among its students, trainees, faculty, and staff as a prerequisite to accomplishing our institutional mission and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.