Postdoc - T-Cell Malignancy Genomics & Immune Profiling

Columbia University Irving Medical Center/VP&S; New York (NY); On-site; USD 65,000 - 85,000; Full time

Benefits offered by this job

Competitive salary with benefits

Job summary

Columbia University Irving Medical Center’s Palomero Laboratory invites applications for a Postdoctoral Research Scientist to study genetics and mechanisms of T-cell leukemia and lymphoma.

The successful candidate will design and perform experiments using mouse models and human samples, with flow cytometry- and single-cell-based immune profiling, collaborating across cancer genetics and translational cores.

Qualifications

• Postdoctoral position focusing on T-cell leukemia/lymphoma research.
• Experience with in vivo and human sample analysis is desirable.
• Ability to design and interpret complex experiments.

Responsibilities

• Design, plan, and execute experiments using genetically engineered and/or xenograft mouse models of T-ALL and PTCL
• Process and analyze primary human patient samples (e.g., peripheral blood, bone marrow, tumor biopsies)
• Perform multi-parameter flow cytometry for immunophenotyping, cell sorting, and functional assays
• Design and analyze single-cell experiments (e.g., scRNA-seq, CITE-seq) to characterize tumor and immune cell populations
• Investigate interactions between tumor cells and the surrounding tumor microenvironment
• Evaluate experimental therapeutics in vitro and in vivo, including preclinical efficacy and mechanism-of-action studies
• Analyze, interpret, and present experimental data clearly to the PI and lab group
• Maintain detailed, accurate, and up-to-date laboratory and animal records
• Contribute to manuscript preparation, grant applications, and conference presentations
• Collaborate productively with other lab members, core facility staff, and outside collaborators
• Help train and mentor junior lab members (graduate students, technicians) as needed

Skills

Mouse models

Flow cytometry

Single-cell sequencing

Job description

Columbia University Irving Medical Center’s Palomero Laboratory invites applications for a Postdoctoral Research Scientist to study genetics and mechanisms of T-cell leukemia and lymphoma.

The successful candidate will design and perform experiments using mouse models and human samples, with flow cytometry- and single-cell-based immune profiling, collaborating across cancer genetics and translational cores.