Postdoc: RBC-Based Liquid Biopsy for Cancer Detection

University of Pennsylvania; Pennsylvania; On-site; USD 55,000 - 70,000; Full time

Job summary

The Mangalmurti Laboratory at the University of Pennsylvania invites applications for a postdoctoral fellow to evaluate red blood cells as a liquid biopsy platform for cancer detection and disease monitoring. The project will investigate rtDNA as a novel substrate for precision oncology, including its biological basis and translational potential.

The fellow will integrate in vitro tumor–RBC co-culture systems, preclinical cancer models, and clinical specimens to define rtDNA acquisition and

Responsibilities

• Lead in vitro tumor–RBC co-culture studies and preclinical models to define rtDNA mechanisms.
• Develop and optimize molecular assays for mutation detection and analytic sensitivity.
• Evaluate RBC-based liquid biopsy feasibility across oncology indications in clinical samples.
• Collaborate with academic and industry partners to advance translational diagnostics.

Job description

The Mangalmurti Laboratory at the University of Pennsylvania invites applications for a postdoctoral fellow to evaluate red blood cells as a liquid biopsy platform for cancer detection and disease monitoring. The project will investigate rtDNA as a novel substrate for precision oncology, including its biological basis and translational potential.

The fellow will integrate in vitro tumor–RBC co-culture systems, preclinical cancer models, and clinical specimens to define rtDNA acquisition and