Postdoc: Lysosomal PD & Rare Disease Research

Denali Therapeutics Inc

South San Francisco (CA)

On-site

USD 72,000 - 88,000

Full time

5 days ago
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Benefits offered by this job

401k
Healthcare coverage
ESPP
Other benefits

Job summary

Denali Therapeutics Inc. is seeking a Postdoctoral Scientist to join the Parkinson's and Rare Disease team in South San Francisco.

You will explore lysosomal dysfunction and its role in Parkinson's disease, working with ASAP collaborators across institutions to understand how disease-linked variants affect lysosomal and lipid homeostasis in CNS cells. You will design cellular assays, perform data analysis, and communicate findings through publications, contributing to a high-impact research

Qualifications

  • PhD required in Cell Biology, Biochemistry, Neuroscience or related field.
  • Experience in membrane trafficking or lysosomal biology is highly desired.
  • Proficiency in live-cell imaging and quantitative image analysis.

Responsibilities

  • Perform research in a dynamic and collaborative environment.
  • Collaborate with colleagues across diverse functional areas to achieve research goals.
  • Make detailed observations, analyze data, interpret results, and communicate clearly.
  • Design and implement cellular assays to probe lysosomal function and identify novel regulators.
  • Attend conferences, write and publish manuscripts in peer-reviewed journals.

Skills

Live-cell imaging
Image analysis
Mammalian cell culture
Transfection
Immunofluorescence
Biochemical techniques

Education

PhD in Cell Biology / Biochemistry / Neuroscience or related field

Tools

Western blotting
Immunofluorescence protocols
Live-cell imaging setups

Job description

Denali Therapeutics Inc. is seeking a Postdoctoral Scientist to join the Parkinson's and Rare Disease team in South San Francisco.

You will explore lysosomal dysfunction and its role in Parkinson's disease, working with ASAP collaborators across institutions to understand how disease-linked variants affect lysosomal and lipid homeostasis in CNS cells. You will design cellular assays, perform data analysis, and communicate findings through publications, contributing to a high-impact research

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