Postdoc: Immuno-Cardiac In Vitro Toxicology Models

Oak Ridge Institute for Science and Education; Arkansas; On-site; USD 22,000 - 33,000; Full time

Job summary

A research opportunity is available immediately with the FDA, NCTR, in Jefferson, Arkansas. The appointed fellow will work on 6PPD-related cardiovascular safety using isogenic immuno-cardiac NAMs, with a monthly stipend commensurate with education and experience.

Applicants should be pursuing or have completed a doctoral degree in a relevant field. The program is administered by ORISE; health insurance is required for participation, and the fellowship term is one year with potential renewal.

Qualifications

• Candidate should be currently pursuing or have received a doctoral degree in one of the relevant fields.

Responsibilities

• Learn to optimize the co-culture system using flow cytometry, immunofluorescence, and microelectrode array (MEA) to characterize the cells.
• Learn to utilize real-time impedance and live-cell imaging to assess the effects of exposure on cells.
• Gain proficiency in the measurement of functional endpoints including beat rate, contractility, rhythm regularity, field potential duration, and arrhythmia susceptibility.
• Gain experience in the analysis of gene expression profiles and identification of affected pathways.
• Gain collaboration skills to formulate hypotheses, record experimental data, prepare reports, and interpret experimental results.
• Present research findings at local and national conferences and in journal publications.

Education

Doctoral degree (pursuing or completed)

Job description

A research opportunity is available immediately with the FDA, NCTR, in Jefferson, Arkansas. The appointed fellow will work on 6PPD-related cardiovascular safety using isogenic immuno-cardiac NAMs, with a monthly stipend commensurate with education and experience.

Applicants should be pursuing or have completed a doctoral degree in a relevant field. The program is administered by ORISE; health insurance is required for participation, and the fellowship term is one year with potential renewal.