Postdoc: Env Vaccine Design & B Cell Immunology

Dana-Farber Cancer Institute; Boston (MA); Hybrid; USD 72,000 - 76,000; Full time

Job summary

The Reinherz lab at Dana-Farber Cancer Institute and Harvard Medical School is recruiting a postdoctoral fellow to study HIV-1 vaccine immunology using an interdisciplinary approach that includes structural biology, molecular biology, biochemistry, and immunology to inform vaccine design.

Located in Boston, the lab focuses on B cell immunodominance, affinity maturation, and novel vaccine strategies, with opportunities to work on in vivo mouse models and advanced immunological techniques within a

Qualifications

• PhD or MD/PhD in biomedical sciences or a closely related field.
• Strong background in immunology, molecular biology and biochemistry.
• Experience with evaluating immune responses including antibody measurement and flow cytometry.
• Peer-reviewed publication record.

Responsibilities

• Design and execute studies on HIV-1 Env vaccine candidates.
• Investigate approaches to enhance B cell affinity maturation and antibody responses.
• Perform mouse immunization studies and in vivo experiments.
• Analyze immune sera and conduct flow cytometry for cell characterization.
• Carry out B cell repertoire analysis and immunohistology experiments.
• Perform molecular cloning, protein expression and purification.
• Maintain cell culture systems and contribute to manuscripts.

Skills

Immunology

Molecular biology

Biochemistry

Communication skills

Independent work

Team collaboration

Education

PhD in biomedical sciences

MD/PhD

Tools

Flow cytometry (FACS)

Mouse models

Molecular cloning

Protein expression

Protein purification

Cell culture

B cell repertoire analysis

Immunohistology

Job description

The Reinherz lab at Dana-Farber Cancer Institute and Harvard Medical School is recruiting a postdoctoral fellow to study HIV-1 vaccine immunology using an interdisciplinary approach that includes structural biology, molecular biology, biochemistry, and immunology to inform vaccine design.

Located in Boston, the lab focuses on B cell immunodominance, affinity maturation, and novel vaccine strategies, with opportunities to work on in vivo mouse models and advanced immunological techniques within a