Postdoc: Cervical Remodeling & Reproductive Genomics

The University of Texas Southwestern Medical Center; Dallas (TX); Híbrido; USD 52.000 - 64.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

PPO medical plan

100% preventive care coverage

Paid Time Off

TRS retirement program

Paid Parental Leave

Descripción de la vacante

UT Southwestern Medical Center in Dallas, TX seeks a postdoctoral fellow in the Mahendroo Lab to study hormone-regulated gene networks driving cervical remodeling during term and preterm birth.

We use mouse, organoid models, single-cell RNA-seq, ATAC-seq, and imaging to uncover clinically relevant mechanisms and train researchers with a strong emphasis on collaboration and innovation.

Formación

• Recent Ph.D. and/or M.D. degree with first-author publication.
• Training in reproductive biology and/or bioinformatics preferred.
• Motivated, creative, and collaborative team member.

Responsabilidades

• Implement computational and experimental approaches to gene regulatory networks.
• Analyze single-cell datasets to study epithelial cell state changes.
• Contribute to postdoctoral training program and collaborative projects.

Conocimientos

Bioinformatics

scRNA-seq analysis

Genomics

Molecular biology

Educación

Ph.D. or M.D.

Herramientas

ChIP-seq

ATAC-seq

RNA-seq

Descripción del empleo

A postdoctoral training position is available in the laboratory ofMala Mahendroo, Ph.D., Professor in the Department of Obstetrics and Gynecology and the Cecil H. and Ida Green Center for Reproductive Biology Sciences at UT Southwestern Medical Center in Dallas, TX. The Center’s mission is to promote cutting-edge, integrative research programs focused on reproductive or developmental biology, signaling, gene regulation, and genome function.

The research in theMahendroo Lab addresses a wide range of questions surrounding the molecular events that drive cervical remodeling in a term pregnancy or in a preterm birth. We utilize mouse and cell/organoid-based models in combination with tissue mechanics, imaging and molecular or genomic approaches to understand fundamental questions that are clinically relevant. Experimental approaches include classical cell and molecular biology techniques, genetic manipulation of mice, genomics and gene regulation (e.g., single cell RNAseq and ATACseq, ChIP-seq,), imaging techniques (second harmonic generation and electron microscopy), proteomics and flow cytometry.

We are seeking postdocs interested in implementing computational and experimental approaches to define hormone-regulated gene regulatory networks that drive cervical remodeling in term and preterm birth. Using single cell datasets, we aim to understand how dynamic changes in epithelial cell states ensure the epithelia provide a customized immune and physical barrier during pregnancy.

Information on our postdoctoral training program, benefits, and a virtual tour can be found at http://www.utsouthwestern.edu/postdocs.

Candidates must hold a recent Ph.D. and/or M.D. degree and first-author publication in peer-reviewed journals. Demonstrated training in the area of reproductive biology and/or bioinformatics is preferred.We especially value motivated, creative, and collaborative team members.

Interested individuals should upload a CV, statement of interest, and a list of 3 references

UTSouthwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. Asan equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis ofrace, color, religion, national origin, sex,sexual orientation, gender identity, gender expression,age, disability, genetic information, citizenship status, or veteran status.

This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.

Appointment rank will be commensurate with academic accomplishment and experience. Consideration may be given to applicants seeking less than a full-time schedule.

To learn more about the benefits UT Southwestern offers, visithttps://www.utsouthwestern.edu/employees/hr-resources/

Benefits

UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:
• PPO medical plan, available day one at no cost for full-time employee-only coverage
• 100% coverage for preventive healthcare – no copay
• Paid Time Off, available day one
• Retirement Programs through the Teacher Retirement System of Texas (TRS)
• Paid Parental Leave Benefit
• Wellness programs
• Tuition Reimbursement
• Public Service Loan Forgiveness (PSLF) Qualified Employer
• Learn more about these and other UTSW employee benefits!