Post-Doctoral Research Fellow- Medical Oncology- Lab of Dr. Claudia Capparelli

Thomas Jefferson University & Jefferson Health; Philadelphia (Philadelphia County); On-site; USD 50,000 - 90,000; Full time

Job summary

An innovative research program is seeking a Postdoctoral Fellow to explore the complexities of melanoma. This role focuses on understanding tumor heterogeneity and plasticity, aiming to develop groundbreaking treatment strategies for patients. The research encompasses a wide range of techniques from molecular biology to clinical applications, providing a unique opportunity to contribute to significant advancements in the field. Join a leading institution dedicated to transforming healthcare and education, where your work can lead to impactful therapeutic approaches and enhance patient outcomes.

Qualifications

• PhD or equivalent required for conducting advanced research.
• Experience in molecular and cellular biology techniques is essential.

Responsibilities

• Investigate tumor heterogeneity and plasticity in melanoma.
• Identify novel treatment strategies and pathway dependencies.

Skills

Molecular Biology

Cellular Biology

3D Cell Culture

Flow Cytometry

Omics Studies

Mouse Models

Education

PhD or equivalent

Job description

Job Details

We are seeking a Postdoctoral Fellow to join our research program to investigate the mechanisms underlying tumor heterogeneity and plasticity in melanoma with the goal of identifying novel treatment strategies for melanoma patients. Our research aims to identify and target pathway dependencies and vulnerabilities in drug-tolerant persister cells to prevent metastasis and improve treatment options. Additional interests include: i) characterizing alterations in the extracellular matrix during drug tolerance development, and ii) investigating therapies that modify the tumor immune microenvironment to enhance immunotherapy responses. Understanding these alterations could lead to new therapeutic approaches for melanoma. Our work spans from molecular mechanisms to clinical applications, utilizing molecular and cellular biology, 3D cell culture, flow cytometry, omics studies, and mouse models.

For more information, please visit: Jefferson Researcher Profile

Job Description

PhD or equivalent

Work Shift

Day shift (United States of America)

Worker Sub Type

Regular

Primary Location Address

951 Locust Street, Philadelphia, Pennsylvania, United States of America

Jefferson, located in the greater Philadelphia region, Lehigh Valley, Northeastern Pennsylvania, and southern New Jersey, is reimagining healthcare and higher education to create unparalleled value. With over 65,000 staff, Jefferson is committed to providing high-quality, compassionate clinical care, advancing health, and fostering education and research. Thomas Jefferson University, established in 1824, comprises 10 colleges and three schools offering over 200 undergraduate and graduate programs to more than 8,300 students. Jefferson Health is a top-ranked not-for-profit healthcare system serving millions annually across 32 hospitals and numerous outpatient locations. Jefferson Health Plans provides broad health coverage options in Pennsylvania and New Jersey for over 35 years.

Jefferson is dedicated to equal opportunity employment and education, regardless of age, race, color, religion, sexual orientation, gender, marital status, pregnancy, national origin, disability, or other protected status.